Protein Alignment dpp and Inhba

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_032406.1
• Gene: Inhba / 16323
• MGIID: 96570
• Length: 424
• Species: Mus musculus
• Alignment Length: 462
• Identity: 104/462 - (22%)
• Similarity: 177/462 - (38%)
• Gaps: 139/462 - (30%)

  Fly   191 PANAKAIIAEQGPSTYSKEALIKDKLKPDPSTLVEIEKSLLSLFNMKRPPKIDR--SKIIIPEPM 253
            |:.|.|.:.:.||::             .|..:..::|.:|::.::|:.|.:.:  .|..:...:
Mouse    36 PSCALATLPKDGPNS-------------QPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAI 87

  Fly   254 KKLYAEIMGH------ELDSVNIPKPGLLTKSANTVRSFTHKDSKIDDRFPHHHRFRLHFDVKSI 312
            :||:...:|.      |.|.....:...|.:..:.:.:|....:.         |..|||::...
Mouse    88 RKLHVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTA---------RKTLHFEISKE 143

  Fly   313 PAD-EKLKAAELQLTRDALSQQVVASRSSANRTRYQVLVY----------------DITRVGVRG 360
            .:| ..::.||:.|         ......|||||.:|.:.                :...:|::|
Mouse   144 GSDLSVVERAEVWL---------FLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGDEAEEMGLKG 199

  Fly   361 QREPSYLLLDTKTVRLNSTD----TVSLDVQPAVDRWLASPQRNYGLLVEVRTVRSLKPAPHHHV 421
            :|  |.|||..|.|....:.    .||..:|..:|:..:|        ::||.
Mouse   200 ER--SELLLSEKVVDARKSTWHIFPVSSSIQRLLDQGKSS--------LDVRI------------ 242

  Fly   422 RLRRSADEAHERWQHKQPLLFTYTDDGRHKARSIRDVSGGEGGGKGG--RNKRQPRRP----TRR 480
                    |.|:.|.....|...   |:.|.:.:......:.|..||  ..|.|..||    ..|
Mouse   243 --------ACEQCQESGASLVLL---GKKKKKEVDGDGKKKDGSDGGLEEEKEQSHRPFLMLQAR 296

  Fly   481 KNHD----------------DTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLA---- 525
            ::.|                :.|.:...:|.|.|:||:|||:||.||.|.||.|:||..:|
Mouse   297 QSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSG 361

  Fly   526 ----------DHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEM 580
                      :|:....|:....|          |:|||||:|..::|||.:|...::.|:.|.|
Mouse   362 SSLSFHSTVINHYRMRGHSPFANL----------KSCCVPTKLRPMSMLYYDDGQNIIKKDIQNM 416

  Fly   581 TVVGCGC 587
            .|..|||
Mouse   417 IVEECGC 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	46/247 (19%)
		TGFB	487..588	CDD:214556	41/115 (36%)
Inhba	NP_032406.1	TGFb_propeptide	56..291	CDD:366248	55/285 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	264..306		9/41 (22%)
		TGF_beta_INHBA	317..424	CDD:381674	41/117 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810