DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dpp and Inha

DIOPT Version :9

Sequence 1:NP_477311.1 Gene:dpp / 33432 FlyBaseID:FBgn0000490 Length:588 Species:Drosophila melanogaster
Sequence 2:NP_034694.3 Gene:Inha / 16322 MGIID:96569 Length:366 Species:Mus musculus


Alignment Length:372 Identity:69/372 - (18%)
Similarity:121/372 - (32%) Gaps:103/372 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   250 PEPMKKL-YAEIMGHELDSVNIP-------KPGL-LTKSANTVRSFTHKDSKIDDRFPHHHRFRL 305
            ||.:::| .|::....||::..|       .||: .....:.|..|.|:.|:             
Mouse    24 PELVRELVLAKVKALFLDALGPPAMDGEGGDPGIRRLPRRHAVGGFMHRTSE------------- 75

  Fly   306 HFDVKSIPADEKLKAAELQLTRDALSQQVVASRSSANRTRYQVLVYDITRVGVRGQREPSYLLLD 370
                   |.:|.:..|.|.....|..:...|:|..|......:.               :|:...
Mouse    76 -------PEEEDVSQAILFPATGATCEDQPAARGLAQEAEEGLF---------------TYVFRP 118

  Fly   371 TKTVRLNSTDTVSLDVQPAVDRWLASPQRNYGLLVEVRTVRSLKPAPHHHVRLRRSADEAHERW- 434
            ::.:|.:...:..|.....:.|...:...:...|:::..:.|..|     :.:..|..:...|| 
Mouse   119 SQHIRSHQVTSAQLWFHTGLGRKSTAAANSSAPLLDLLVLSSGGP-----MAVPVSLGQGPPRWA 178

  Fly   435 -------------------------------QHKQPLLFTYTDDGRHKARSIRDVSGGEGGGKGG 468
                                           ....|.|..:|     :||:   .|.||...:..
Mouse   179 VLHLAASAFPLLTHPILVLLLRCPLCSCSGRPETTPFLVAHT-----RARA---PSAGERARRST 235

  Fly   469 RNKRQP---------RRPTRRKNHDDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPL 524
            .:...|         :||.........|.|.:|.:.|.::|||.|||.|..:..:||||.|..|.
Mouse   236 PSVPWPWSPAALRLLQRPPEEPAAHAFCHRAALNISFQELGWDRWIVHPPSFIFHYCHGSCGMPT 300

  Fly   525 AD---HFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLND 568
            :|   .........||.|.  :.||..|....:|..:.|:.:...:|
Mouse   301 SDLPLPVPGVPPTPVQPLF--LVPGAKPCCAALPGSMRSLRVRTTSD 345

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dppNP_477311.1 TGFb_propeptide 225..444 CDD:279078 33/234 (14%)
TGFB 487..588 CDD:214556 27/85 (32%)
InhaNP_034694.3 TGF_beta 263..366 CDD:295336 27/85 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3900
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.