Protein Alignment dpp and Gdf9

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_032136.2
• Gene: Gdf9 / 14566
• MGIID: 95692
• Length: 441
• Species: Mus musculus
• Alignment Length: 491
• Identity: 115/491 - (23%)
• Similarity: 174/491 - (35%)
• Gaps: 133/491 - (27%)

  Fly   157 ASASTESHQSSSIESIFVE-EP---TLVLDREVASINVPANAKAIIAEQGPSTYSKEALIKDKLK 217
            :.||||..||.:.|::..| :|   .|.:|....|..:|...|.:...:|.:         .||:
Mouse    25 SQASTEESQSGASENVESEADPWSLLLPVDGTDRSGLLPPLFKVLSDRRGET---------PKLQ 80

  Fly   218 PDPSTLVEIEKSLLSLFNMKRPPKIDRSKIIIPEPMKKLYAEIMGHELDSVNIPKPGLLTKSANT 282
            ||...|..                           |||||......|    .:|||. .:...||
Mouse    81 PDSRALYY---------------------------MKKLYKTYATKE----GVPKPS-RSHLYNT 113

  Fly   283 VRSFT-------HKDSKIDDRFPHHHRFRLHFDVKSIPADEKLKAAELQLTRDALSQQVVASRSS 340
            ||.|:       ...:::....|   ...|.|::..:.|.|.|..:.|..|   |:..  ||.||
Mouse   114 VRLFSPCAQQEQAPSNQVTGPLP---MVDLLFNLDRVTAMEHLLKSVLLYT---LNNS--ASSSS 170

  Fly   341 ANRTRYQVLVYDITRVGVRGQREP-SYLLLDTKTVRLNSTDTVSLDVQPAVDRWLASPQRNYGLL 404
            .......::|.:....|....|.| |:.|   |..|....|..|| :||.|    .|.:|:..|.
Mouse   171 TVTCMCDLVVKEAMSSGRAPPRAPYSFTL---KKHRWIEIDVTSL-LQPLV----TSSERSIHLS 227

  Fly   405 VEVRTVRSLKP-----------APHHHVRLRRSADEAHERWQHKQ----PLLFTYTDDGRHKARS 454
            |.....:...|           .|...:.|..::.:|:..||..|    ||        :|.
Mouse   228 VNFTCTKDQVPEDGVFSMPLSVPPSLILYLNDTSTQAYHSWQSLQSTWRPL--------QHP--- 281

  Fly   455 IRDVSGGEGGGKGGRNKRQ----PRRPTRRKNH----------------------------DDTC 487
                  |:.|......|.:    .|.|.||:..                            .:.|
Mouse   282 ------GQAGVAARPVKEEAIEVERSPRRRRGQKAIRSEAKGPLLTASFNLSEYFKQFLFPQNEC 340

  Fly   488 RRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVPKAC 552
            ..|...:.||.:.||:|||||..|:..||.|.||..:...:.|..|.:||.::.......||:..
Mouse   341 ELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVRHRYGSPVHTMVQNIIYEKLDPSVPRPS 405

  Fly   553 CVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGCR 588
            |||.:...:::|.:....::..|.|::|....|.||
Mouse   406 CVPGKYSPLSVLTIEPDGSIAYKEYEDMIATRCTCR 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	54/241 (22%)
		TGFB	487..588	CDD:214556	31/100 (31%)
Gdf9	NP_032136.2	TGF_beta_GDF9	336..441	CDD:381673	31/104 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810