Protein Alignment dpp and Gdf3

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_032134.2
• Gene: Gdf3 / 14562
• MGIID: 95686
• Length: 366
• Species: Mus musculus
• Alignment Length: 400
• Identity: 104/400 - (26%)
• Similarity: 169/400 - (42%)
• Gaps: 100/400 - (25%)

  Fly   227 EKSLLSLFNMKRPPKIDRSKIIIPEPMKKL-----------------YAEIMGHELDSVN-IPKP 273
            :..||....:::.|...|.: .:|..::|:                 |.:.:|...:.:. :|..
Mouse    27 DSDLLQFLGLEKAPSPHRFQ-PVPRVLRKIIRAREAAAASGASQDLCYVKELGVRGNLLQLLPDQ 90

  Fly   274 GLLTKSANTVRSFTHKDSKIDDRFPHHHRFRLHFDVKSIPADEKLKAAELQLTRDALSQQVVASR 338
            |..   .||.:.|  :|.....:.       |:|::.:|  .||.|....|||.|      :..|
Mouse    91 GFF---LNTQKPF--QDGSCLQKV-------LYFNLSAI--KEKAKLTMAQLTLD------LGPR 135

  Fly   339 SSAN-RTRYQVLVYDITRVGVRGQREPSY-LLLDTKTVRLNSTDTVSLDVQPAVDRWLASPQRNY 401
            |..| |....|.:..:...||.|:..|.. .||..::|. .....:..::|.|:..|.::..:|.
Mouse   136 SYYNLRPELVVALSVVQDRGVWGRSHPKVGRLLFLRSVP-GPQGQLQFNLQGALKDWSSNRLKNL 199

  Fly   402 GLLVEVR---------TVRSLKPAPHHHVRLRRSADEAHERWQHKQPLLFTYTDDGRHKARSIRD 457
            .|.:|:.         ||:...|..    ||.||.        |...|:.|......|
Mouse   200 DLHLEILVKEDRYSRVTVQPENPCD----RLLRSL--------HASLLVVTLNPKHCH------- 245

  Fly   458 VSGGEGGGKGGRNKRQPRRPTRRKNH----------DDTCRRHSLYVDFSDVGWDDWIVAPLGYD 512
                               |:.||..          .:.|.||.|:::|.|:||..|::||.|:.
Mouse   246 -------------------PSSRKRRAAISVPKGFCRNFCHRHQLFINFQDLGWHKWVIAPKGFM 291

  Fly   513 AYYCHGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNY 577
            |.||||:|||.:..:.||:|:|.:|.|::..:| |||||.||||:|..::|||.:....|:|::|
Mouse   292 ANYCHGECPFSMTTYLNSSNYAFMQALMHMADP-KVPKAVCVPTKLSPISMLYQDSDKNVILRHY 355

  Fly   578 QEMTVVGCGC 587
            ::|.|..|||
Mouse   356 EDMVVDECGC 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	51/245 (21%)
		TGFB	487..588	CDD:214556	47/100 (47%)
Gdf3	NP_032134.2	TGFb_propeptide	<110..204	CDD:279078	27/102 (26%)
		TGFB	266..366	CDD:214556	47/100 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	4	3.770