Protein Alignment dpp and Gdf11

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_034402.1
• Gene: Gdf11 / 14561
• MGIID: 1338027
• Length: 405
• Species: Mus musculus
• Alignment Length: 427
• Identity: 99/427 - (23%)
• Similarity: 154/427 - (36%)
• Gaps: 85/427 - (19%)

  Fly   192 ANAKAIIAEQGPSTYSKEALIKDKLKPDPS--------------TLVEIEKSLLSLFNMKRPPKI 242
            |.|.|..|..|....|:.|   ....|:|.              .|..|:..:||...:|..|.|
Mouse    32 AAAAAAAAGVGGERSSRPA---PSAPPEPDGCPVCVWRQHSRELRLESIKSQILSKLRLKEAPNI 93

  Fly   243 DRS--KIIIPE--PMKKL--YAEIMGHELDSVNIPKPGLLTKSANTVRSFTHK-DSKID-DRFPH 299
            .|.  |.::|:  |::::  ..:..|..|...:..:......:..||.|...: |..:. |..|.
Mouse    94 SREVVKQLLPKAPPLQQILDLHDFQGDALQPEDFLEEDEYHATTETVISMAQETDPAVQTDGSPL 158

  Fly   300 HHRFRLHFDVKSIPADEKLKAAELQLTRDALSQQVVASRSSANRTRYQVLVYDITRVGVRGQREP 364
            ...|  ||..| :...:.|||......|.......|..:.    .|.:.|..:.|..|..|.|.
Mouse   159 CCHF--HFSPK-VMFTKVLKAQLWVYLRPVPRPATVYLQI----LRLKPLTGEGTAGGGGGGRR- 215

  Fly   365 SYLLLDTKTVRLNSTD--TVSLDVQPAVDRWLASPQRNYGLLVEV-------RTVRSLKPAPHHH 420
             ::.:.:..:.|:|..  ..|:|.:..:..|...||.|:|:.:..       ..|.||.|..
Mouse   216 -HIRIRSLKIELHSRSGHWQSIDFKQVLHSWFRQPQSNWGIEINAFDPSGTDLAVTSLGPGA--- 276

  Fly   421 VRLRRSADEAHERWQHKQPLLFTYTDDGRHKARSIRDVSGGEGGGKGGRNKRQPRRPTRRKNHDD 485
                                      :|.|....:|.:...:      |::|.........:.:.
Mouse   277 --------------------------EGLHPFMELRVLENTK------RSRRNLGLDCDEHSSES 309

  Fly   486 TCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVPK 550
            .|.|:.|.|||...|| |||:||..|.|.||.|:|.:.....:..|:      ||...||.....
Mouse   310 RCCRYPLTVDFEAFGW-DWIIAPKRYKANYCSGQCEYMFMQKYPHTH------LVQQANPRGSAG 367

  Fly   551 ACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGC 587
            .||.||::..:.|||.||:..::......|.|..|||
Mouse   368 PCCTPTKMSPINMLYFNDKQQIIYGKIPGMVVDRCGC 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	46/235 (20%)
		TGFB	487..588	CDD:214556	38/101 (38%)
Gdf11	NP_034402.1	TGFb_propeptide	59..283	CDD:279078	49/261 (19%)
		TGFB	311..405	CDD:214556	38/101 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810