Protein Alignment dpp and Gdf1

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001156754.1
• Gene: Gdf1 / 14559
• MGIID: 95683
• Length: 357
• Species: Mus musculus
• Alignment Length: 437
• Identity: 103/437 - (23%)
• Similarity: 160/437 - (36%)
• Gaps: 149/437 - (34%)

  Fly   203 PSTYSKEALIKDKLKPDPSTLVEIEKSLLSLFNMKRPPKI------------------DRSKIII 249
            |||         .|.|.|:::.. ..:||.:..:...|:.                  |..:..:
Mouse    19 PST---------TLAPAPASMGP-AAALLQVLGLPEAPRSVPTHRPVPPVMWRLFRRRDPQEARV 73

  Fly   250 PEPMKKLYAEIMGHELDSV-NIPKPGLLTKSANTVRSFTHKDSKIDDRFPHHHRFRLHFDVKSIP 313
            ..|::..:.|.:|...:.| :||..||.::.|...|:        ....|   .:.:.||:.::.
Mouse    74 GRPLRPCHVEELGVAGNIVRHIPDSGLSSRPAQPART--------SGLCP---EWTVVFDLSNVE 127

  Fly   314 ADEKLKAAELQLTRDALSQQV------VASRSSANRTRYQVLVYDITRVGVRGQREPSYL----L 368
            ..|:...|.|:|..:|.|:..      ||..:.|.....::|         |....|..|    |
Mouse   128 PTERPTRARLELRLEAESEDTGGWELSVALWADAEHPGPELL---------RVPAPPGVLLRADL 183

  Fly   369 LDTK---------TVRLNSTDTVSLDVQPAVDRWLASPQRNYGLLVEVRTVRSLKPAPHHHVRLR 424
            |.|.         ||||      :|.:.|...  .|..:.....|:.|.....|.|.|    |||
Mouse   184 LGTAVAANASVPCTVRL------ALSLHPGAT--AACGRLAEASLLLVTLDPRLCPLP----RLR 236

  Fly   425 RSADEAHERWQHKQPLLFTYTDDGRHKARSIRDVSGGEGGGKGGRNKRQPRRPTRRKNHDDTCRR 489
            |          |.:|.:                    |.|..|                  |||.
Mouse   237 R----------HTEPRV--------------------EVGPVG------------------TCRT 253

  Fly   490 HSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNST----------NHAVVQTLVNNMN 544
            ..|:|.|.:|||..|::||.|:.|.:|.|.|..|      .|          ||||::.|::...
Mouse   254 RRLHVSFREVGWHRWVIAPRGFLANFCQGTCALP------ETLRGPGGPPALNHAVLRALMHAAA 312

  Fly   545 PGKVPKA---CCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGCR 588
            |  .|.|   ||||.:|..:::|:.::...|||::|::|.|..||||
Mouse   313 P--TPGAGSPCCVPERLSPISVLFFDNSDNVVLRHYEDMVVDECGCR 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	51/256 (20%)
		TGFB	487..588	CDD:214556	40/113 (35%)
Gdf1	NP_001156754.1	TGFb_propeptide	36..>141	CDD:279078	21/115 (18%)
		TGFB	251..357	CDD:214556	40/113 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870