Protein Alignment dpp and Lefty1

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_034224.1
• Gene: Lefty1 / 13590
• MGIID: 107405
• Length: 368
• Species: Mus musculus
• Alignment Length: 389
• Identity: 85/389 - (21%)
• Similarity: 148/389 - (38%)
• Gaps: 85/389 - (21%)

  Fly   225 EIEKSLLSLFNMKRPPKIDRSKI---IIPEPMKKLYAEIMGHELDSVNIPKPGLLTKSANTVRSF 286
            :|..|||....:.:||.:|::.:   :||..::..|..::.|.            ..|.:..:.|
Mouse    26 QILGSLLQQLQLDQPPVLDKADVEGMVIPSHVRTQYVALLQHS------------HASRSRGKRF 78

  Fly   287 THKDSKIDDRF------PHHHRFRLHFDVKSIPADEKLKAAELQL-----TRDALSQQVVASRSS 340
            :....::..||      .|...|.:.   :.:|.:.:|..|.|:|     .|.||.:|   .|.|
Mouse    79 SQNLREVAGRFLVSETSTHLLVFGME---QRLPPNSELVQAVLRLFQEPVPRTALRRQ---KRLS 137

  Fly   341 ANRTRYQVLVYDITRVGVRGQREPSYLLLDTKTVRLNSTDTVSLDVQPAVDRWLASPQRNYGLLV 405
            .:..|.:|.: :..|....|....:  |:|::.|.::.:...:.||..||:.|....:....||:
Mouse   138 PHSARARVTI-EWLRFRDDGSNRTA--LIDSRLVSIHESGWKAFDVTEAVNFWQQLSRPRQPLLL 199

  Fly   406 EVRTVRS-LKPAP-HHHVRLRRSADEAHERWQHKQPLLFTYTDDGRHKARSIRDVSGGEGGGKGG 468
            :|...|. |.|.. ..|..:|.:|....:.....:|.|..:|.|       ::|.        |.
Mouse   200 QVSVQREHLGPGTWSSHKLVRFAAQGTPDGKGQGEPQLELHTLD-------LKDY--------GA 249

  Fly   469 RNKRQPRRPTRRKNHDDTCRRHSLYVDFSDVGW-DDWIVAPLGYDAYYCHGKC---PFPLADHFN 529
            :....|..|.   .....|.|..:|:|...:.| ::||:.|.|:..|.|.|.|   |..|...:
Mouse   250 QGNCDPEAPV---TEGTRCCRQEMYLDLQGMKWAENWILEPPGFLTYECVGSCLQLPESLTSRW- 310

  Fly   530 STNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQ------STVVLKNYQEMTVVGCGC 587
                           |...|:. ||.:::.|:.|:....:      ..|.|.|   |.|..|.|
Mouse   311 ---------------PFLGPRQ-CVASEMTSLPMIVSVKEGGRTRPQVVSLPN---MRVQTCSC 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	51/234 (22%)
		TGFB	487..588	CDD:214556	28/111 (25%)
Lefty1	NP_034224.1	TGFb_propeptide	<106..211	CDD:279078	28/110 (25%)
		TGF_beta	263..355	CDD:278448	27/111 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810