Protein Alignment dpp and Bmp8a

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001242948.1
• Gene: Bmp8a / 12163
• MGIID: 104515
• Length: 412
• Species: Mus musculus
• Alignment Length: 406
• Identity: 121/406 - (29%)
• Similarity: 185/406 - (45%)
• Gaps: 79/406 - (19%)

  Fly   225 EIEKSLLSLFNM---KRP---PKIDRSKIIIPEPMKKLYAEIMGHEL---DSVNIPKPGLLTKSA 280
            ::::.:|::..:   .||   |...|.....|..|..||     |.:   |....|:..|  ..|
Mouse    42 DMQREILAVLGLPGRPRPRAQPAAARQPASAPLFMLDLY-----HAMTDDDDGGPPQAHL--GRA 99

  Fly   281 NTVRSFTH---KDSKIDDRFPHHHRFRLHFDVKSIPADEKLKAAELQLTRDALSQQVVASRSSAN 342
            :.|.||.:   :|..:..:.||...|  |||:..|||.|.:.|||.::.::..:..:
Mouse   100 DLVMSFVNMVERDRTLGYQEPHWKEF--HFDLTQIPAGEAVTAAEFRIYKEPSTHPL-------- 154

  Fly   343 RTRYQVLVYDITRVGVRGQREPSYLLLDTKTVRLNSTDTVSLDVQPAVDRWLASPQRNYGLLVEV 407
            .|...:.::::  |.....||.....||.:|:|......:.||:..|.||||.:..::.||.:.|
Mouse   155 NTTLHISMFEV--VQEHSNRESDLFFLDLQTLRSGDEGWLVLDITAASDRWLLNHHKDLGLRLYV 217

  Fly   408 RTVRSLKPAPHHHVRLRRSADEAHERWQHKQPLLFTYTDDGRHKARSIRDVSGGEGGGKGGR--N 470
            .|.......|.....|.|.|..:      :||.:.|:....:...|:.|          ..|  .
Mouse   218 ETADGHSMDPGLAGLLGRQAPRS------RQPFMVTFFRASQSPVRAPR----------AARPLK 266

  Fly   471 KRQPRRPTRRKNH--------DD--------TCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGK 519
            :|||:: |....|        ||        .||||.|||.|.|:||.||::||.||.||||.|:
Mouse   267 RRQPKK-TNELPHPNKLPGIFDDGHGSRGREVCRRHELYVSFRDLGWLDWVIAPQGYSAYYCEGE 330

  Fly   520 CPFPLADHFNSTNHAVVQTLVNN-------------MNPGKVPKACCVPTQLDSVAMLYLNDQST 571
            |.|||....|:||||::|:||:.             |.|..||||||.||:|.:.::||.:..:.
Mouse   331 CAFPLDSCMNATNHAILQSLVSTTVACCDRWSGVHLMKPDVVPKACCAPTKLSATSVLYYDSSNN 395

  Fly   572 VVLKNYQEMTVVGCGC 587
            |:|:.::.|.|..|||
Mouse   396 VILRKHRNMVVKACGC 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	56/230 (24%)
		TGFB	487..588	CDD:214556	54/114 (47%)
Bmp8a	NP_001242948.1	TGFb_propeptide	32..248	CDD:279078	56/230 (24%)
		TGF_beta	298..411	CDD:278448	52/112 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1063560at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X157
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820