Protein Alignment dpp and Bmp7

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_031583.2
• Gene: Bmp7 / 12162
• MGIID: 103302
• Length: 430
• Species: Mus musculus
• Alignment Length: 498
• Identity: 138/498 - (27%)
• Similarity: 208/498 - (41%)
• Gaps: 152/498 - (30%)

  Fly   131 HNKMAVKEQRSHHKK-------SHHHRSH-QPKQASASTESHQSSSIESIFVEEPTLVLDREVAS 187
            |.::..:|:|...::       .|..|.| |.|..||                 |..:||.
Mouse    43 HRRLRSQERREMQREILSILGLPHRPRPHLQGKHNSA-----------------PMFMLDL---- 86

  Fly   188 INVPANAKAIIAEQGPS----TYSKEALIKDKLKPDPSTLVEIEKSLLSLFNMKRPP--KIDRSK 246
                .||.| :.|.||.    :|..:|                      :|:.:.||  .:..|.
Mouse    87 ----YNAMA-VEESGPDGQGFSYPYKA----------------------VFSTQGPPLASLQDSH 124

  Fly   247 IIIPEPMKKLYAEIMGHELDSVNIPKPGLLTKSANTVRSFTHKDSKIDDRFPHHHRFRLHFDVKS 311
            .:....|...:..::.|:                   :.|.|      .|: ||..||  ||:..
Mouse   125 FLTDADMVMSFVNLVEHD-------------------KEFFH------PRY-HHREFR--FDLSK 161

  Fly   312 IPADEKLKAAELQLTRDALSQQVVASRSSANRTRYQVLVYDITRVGVRGQREPSYLLLDTKTVRL 376
            ||..|.:.|||.::.:|.:       |...:...:|:.||.:.:  ....||....|||::|:..
Mouse   162 IPEGEAVTAAEFRIYKDYI-------RERFDNETFQITVYQVLQ--EHSGRESDLFLLDSRTIWA 217

  Fly   377 NSTDTVSLDVQPAVDRWLASPQRNYGLLVEVRTV--RSLKP---------APHHHVRLRRSADEA 430
            :....:..|:....:.|:.:|:.|.||.:.|.|:  :|:.|         .|
Mouse   218 SEEGWLVFDITATSNHWVVNPRHNLGLQLSVETLDGQSINPKLAGLIGRHGP------------- 269

  Fly   431 HERWQHKQPLLFTYTDDGRHKARSIRDVSGGEGGGKGGRNKRQPRRPTRRKNHD----------- 484
                |:|||.:..:........||||..        ||:.:.|.|..| .||.:
Mouse   270 ----QNKQPFMVAFFKATEVHLRSIRST--------GGKQRSQNRSKT-PKNQEALRMASVAENS 321

  Fly   485 -----DTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMN 544
                 ..|::|.|||.|.|:||.|||:||.||.||||.|:|.|||..:.|:||||:|||||:.:|
Mouse   322 SSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFIN 386

  Fly   545 PGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGC 587
            |..|||.||.||||:::::||.:|.|.|:||.|:.|.|..|||
Mouse   387 PDTVPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGC 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	47/231 (20%)
		TGFB	487..588	CDD:214556	59/101 (58%)
Bmp7	NP_031583.2	TGFb_propeptide	35..279	CDD:395559	68/337 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	290..310		9/28 (32%)
		TGF_beta_BMP7	324..430	CDD:381667	59/106 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X157
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810