Protein Alignment dpp and Bmp10

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_033886.2
• Gene: Bmp10 / 12154
• MGIID: 1338820
• Length: 421
• Species: Mus musculus
• Alignment Length: 399
• Identity: 114/399 - (28%)
• Similarity: 186/399 - (46%)
• Gaps: 56/399 - (14%)

  Fly   219 DPSTLVE-IEKSLLSLFNMKRPPKIDRSKIIIPEPMKKLYAEIMGHELDSVNIPKPGLLTKSANT 282
            |.:||:: ::...|...|:...|..|..::..||.|.:||.:.   ..|..::|       |||.
Mouse    50 DFNTLLQSMKNEFLKTLNLSDIPVQDTGRVDPPEYMLELYNKF---ATDRTSMP-------SANI 104

  Fly   283 VRSFTHKDSKIDD-RFPHHHRFRLHFDVKSIPADEKLKAAELQL----TRDALSQQVVASRSSAN 342
            :|||.::|..... .|....::.|.|:| |||..|::..|||:|    .||.:....|..:
Mouse   105 IRSFKNEDLFSQPVTFNGLRKYPLLFNV-SIPHHEEVVMAELRLYTLVQRDRMMYDGVDRK---- 164

  Fly   343 RTRYQVLVYDITRVGVRGQREPSYLLLDTKTVRLNSTDTVSLDVQPAVDRWLASPQRNYGLLVEV 407
                 :.::::.......:.|.|.|:|.:..:...:::..:.||..|..||..|....:.|.:.:
Mouse   165 -----ITIFEVLESADGSEEERSMLVLVSTEIYGTNSEWETFDVTDATRRWQKSGPSTHQLEIHI 224

  Fly   408 RTVRS-LKPAPHHHVRLRRSADEAHERWQHKQPLLFTYTDD---GRHKARSIRDV---------- 458
            .:.:: .:......:.:..||...|:      |||..::||   .:.:...:.::
Mouse   225 ESRQNQAEDTGRGQLEIDMSAQNKHD------PLLVVFSDDQSNDKEQKEELNELITHEQDLDLD 283

  Fly   459 SGGEGGGKGGRNKRQPR--------RPTRRKNHDDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYY 515
            |.....|.......|.|        ...||....:.|::..||:||.::|||.||:||.||:||.
Mouse   284 SDAFFSGPDEEALLQMRSNMIDDSSARIRRNAKGNYCKKTPLYIDFKEIGWDSWIIAPPGYEAYE 348

  Fly   516 CHGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLK-NYQE 579
            |.|.|.:|||:|...|.||::|.||:..|..|..|||||||:||.:::||| |:..|..| .|:.
Mouse   349 CRGVCNYPLAEHLTPTKHAIIQALVHLKNSQKASKACCVPTKLDPISILYL-DKGVVTYKFKYEG 412

  Fly   580 MTVVGCGCR 588
            |.|..||||
Mouse   413 MAVSECGCR 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	50/225 (22%)
		TGFB	487..588	CDD:214556	51/101 (50%)
Bmp10	NP_033886.2	TGFb_propeptide	55..256	CDD:279078	50/226 (22%)
		TGF_beta	318..420	CDD:278448	50/102 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810