Protein Alignment dpp and nodal5

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: XP_002945280.2
• Gene: nodal5 / 100495007
• XenbaseID: XB-GENE-483267
• Length: 386
• Species: Xenopus tropicalis
• Alignment Length: 440
• Identity: 105/440 - (23%)
• Similarity: 171/440 - (38%)
• Gaps: 139/440 - (31%)

  Fly   222 TLVEIEKSLLSLFNMK--RPP------KIDRSKII----IPEPMK-KLYAEIMGHELDSVNIPKP 273
            |::.:...:.:|.:.|  |.|      :::.|.::    :|..|| .:|...|...|.|.....|
 Frog    11 TILSLGHGMPTLLHTKEARFPLQGSTQRLESSSVLHGKRLPHDMKYPVYMVQMYQNLISGTDKSP 75

  Fly   274 GL----LTKSANTVRSFTHKD-SKIDDRFPHHHRFRLHFDVKSIPADEKLKAAELQLTRDALSQQ 333
            .:    :.:.::||.|...|. :::|.      ::.|.||:.||....:|:.|||::...:|.
 Frog    76 SVRGEPVLQESDTVLSLIAKGCTQVDS------QWILSFDMSSISISSELRLAELRIHLPSLE-- 132

  Fly   334 VVASRSSANRTRYQVLVYDITRVGVRGQREPSYLLLDTKTVRLNSTDTVS---LDVQPAVDRWL- 394
                       |:|.:..||..  .:|..|..:  |.:.|:....|...|   .:|...:.|:|
 Frog   133 -----------RFQNVTLDIYH--TKGNLEKFF--LGSLTIDFPGTSGSSWKVFNVTQMLQRYLY 182

  Fly   395 --------------ASPQRNY-----GLLVE----------------------VRTVRSLK---- 414
                          |:.|...     |||.|                      :.|..|.|
 Frog   183 QKESFSSDKYTQPKATSQAEQKISCNGLLSERIMLMVFSTDKPSSKLTGSTSLIETAESSKYVIT 247

  Fly   415 ------PAPHHHVRLRRSADEAHERWQHKQPLLFTYTDDGRHKARSIRDVSGGEGGGKGGRNKRQ 473
                  .....|.|.|.:.:.......|.||:                      |.||
 Frog   248 EADTRETGKRRHRRNRYALNSIIRSSFHSQPV----------------------GDGK------- 283

  Fly   474 PRRPTRRKNHDDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQT 538
                       ..|||..:.|||..:||.|.|:.|..::||.|.|.||.||.::|..||||.:::
 Frog   284 -----------TLCRRVDMIVDFEKIGWSDRIIYPKRFNAYRCEGSCPIPLNENFKPTNHAYIKS 337

  Fly   539 LVNNMNPGKVPKACCVPTQLDSVAML-YLNDQSTVVLKNYQEMTVVGCGC 587
            |||:.|||:|....|:|.::..::|| |..|:  :|||::::|.|..|||
 Frog   338 LVNHFNPGRVECPSCIPVKMRPLSMLMYEGDE--IVLKHHEDMIVEECGC 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	56/291 (19%)
		TGFB	487..588	CDD:214556	45/102 (44%)
nodal5	XP_002945280.2	TGFb_propeptide	51..186	CDD:366248	36/157 (23%)
		TGF_beta_NODAL	284..385	CDD:381637	43/102 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910