Protein Alignment dpp and inhbc

DIOPT Version :10

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: XP_002939470.1
• Gene: inhbc / 100493888
• XenbaseID: XB-GENE-494358
• Length: 367
• Species: Xenopus tropicalis
• Alignment Length: 419
• Identity: 92/419 - (21%)
• Similarity: 153/419 - (36%)
• Gaps: 114/419 - (27%)

  Fly   207 SKEALIKDKLKP-----DPSTLVEIEK-SLLSLFNMKRPPKIDRSKIIIPEPMKKLYAEIMGHEL 265
            |.:.|.|....|     |...::|:.| .:|...::|..|.|..     |.|     ...:.:.|
 Frog    24 STQGLTKKSQCPSCGVQDKEVMMELAKQQILQKLHLKERPNITH-----PVP-----RGAVANAL 78

  Fly   266 DSVNIPKP------GLLTKSANTVRSFTHKDSKIDDRFPHHHRFRLHFDVKSIP----ADEKLKA 320
            ..:::.||      |.:...:||..:.|.:.|               :::.|..    ::|....
 Frog    79 RRLHLNKPRMEGLFGSINWDSNTENTETDQQS---------------YEIISFAETEYSNEISTT 128

  Fly   321 AELQLTRD-ALSQQVVASR----SSANRTRYQVLVYDITRVGVRGQREPSYLLLDTKTVRLNSTD 380
            ...|.||| ..|..|:.:.    ..||||..|                       .:|:||..
 Frog   129 LNFQFTRDREQSTHVLQAHLWLFFKANRTSQQ-----------------------NETIRLYL-- 168

  Fly   381 TVSLDVQPAVDRWLASPQRNYGLLVEVR-----------TVRSLKPAPHHHVRLRRSADEAHERW 434
                 ||.|..|.:...::    |:|.|           |:::.....:..::|..:.:...:
 Frog   169 -----VQEANSRRILISEK----LIEPRWTGWQTFSLKSTLQAFFDGGNKSLQLELNCEGCQD-- 222

  Fly   435 QHKQPLLFTYTDDGRHKARSIRDVSGGEGGGKGGRNKRQPRRPTRRK----NHDDTCRRHSLYVD 495
               .|:|....|.  |:...:......|          |....|:|.    .:.:.|.|...|||
 Frog   223 ---APVLINLNDS--HQPFLVAQAKVHE----------QSHHATKRSLNCDQNSNLCCRKDYYVD 272

  Fly   496 FSDVGWDDWIVAPLGYDAYYCHGKCPFPL--ADHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQL 558
            |.|:||:|||:.|.||...||.|.||..:  |....::.|..|..|:...|......:|||||:.
 Frog   273 FKDIGWNDWIIKPEGYQINYCMGLCPMHIAGAPGMAASFHTTVFNLIKANNIQNAVNSCCVPTKR 337

  Fly   559 DSVAMLYLNDQSTVVLKNYQEMTVVGCGC 587
            ..::|||.:..:.::..:..:|.|..|||
 Frog   338 RPLSMLYFDRNNNILKTDIADMIVEACGC 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:480997	43/245 (18%)
		TGF_beta_DPP	480..588	CDD:381662	39/114 (34%)
inhbc	XP_002939470.1	TGFb_propeptide	41..239	CDD:480997	46/263 (17%)
		TGF_beta_INHBC_E	264..367	CDD:381676	38/103 (37%)