Protein Alignment dpp and bmp10

DIOPT Version :10

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: XP_002935357.1
• Gene: bmp10 / 100487047
• XenbaseID: XB-GENE-478875
• Length: 421
• Species: Xenopus tropicalis
• Alignment Length: 413
• Identity: 127/413 - (30%)
• Similarity: 185/413 - (44%)
• Gaps: 80/413 - (19%)

  Fly   212 IKDKLKPDPSTLVEIEKSL-LSLFNMKRPPKIDRSKIIIPEPMKKLYAEIMGHELDSVNIPKPGL 275
            :::.:|.|      |.::| ||...::.|.|:|.     ||.|.:||...   ..|...:|
 Frog    53 LRETMKDD------ILRTLNLSGIPVQPPVKVDP-----PEYMLELYNRF---AKDRTTMP---- 99

  Fly   276 LTKSANTVRSFTHKDSKIDDRFPHH-----HRFRLHFDVKSIPADEKLKAAELQLTRDALSQQVV 335
               |||.||||.::|..:    |:.     .|:.|.|:| |||..|:|..|||:     |...|.
 Frog   100 ---SANIVRSFKNEDFSM----PYSDAMGVRRYALLFNV-SIPHHEELVMAELK-----LYMMVP 151

  Fly   336 ASRSSANRTRYQVLVYDITRVG---VRGQREPSYLLLDTKTVRLNSTDTVSLDVQPAVDRWLASP 397
            ..|........:|.||:|...|   :|.....|.|:..|      |::....|:..||.||..|.
 Frog   152 RERMKFEGVGRKVTVYEIYSEGEDTIRAVELASRLVYKT------SSEWQMFDITEAVRRWSRSE 210

  Fly   398 QRNYGLLVEVRTVR-SLKPAPHHHVRLRRSADEAHERWQHKQPLLFTYTDDGRHKARSIR----- 456
            ...:.|.|:|:... .|:.:...::.:....:..||      |.|..::||.....:..:
 Frog   211 FATHRLEVQVQNPDVDLEGSGEGNLDIEVRPESKHE------PFLVVFSDDQSSDKKEEKEELEE 269

  Fly   457 --------DVSGGE----GGGKGGRNKRQPR--------RPTRRKNHDDTCRRHSLYVDFSDVGW 501
                    |...||    |.|....:..|.|        ...||....:.|::..||:||.::||
 Frog   270 MITHEEGLDQENGEDIGLGNGLSEESLLQMRSNIIYDASSRIRRNAKGNYCKKTPLYIDFGEIGW 334

  Fly   502 DDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYL 566
            :.||:||.||:||.|.|.|.:||.:|...|.||:|||||:..|..|..|||||.|:||.:::|||
 Frog   335 NSWIIAPQGYEAYECRGVCSYPLTEHVTPTKHAIVQTLVHMKNAQKASKACCVATKLDPISILYL 399

  Fly   567 NDQSTVVLK-NYQEMTVVGCGCR 588
             |...|..| .|:.|.|..||||
 Frog   400 -DAGVVTYKFKYEGMVVAECGCR 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:480997	62/228 (27%)
		TGF_beta_DPP	480..588	CDD:381662	51/108 (47%)
bmp10	XP_002935357.1	TGFb_propeptide	54..252	CDD:480997	64/240 (27%)
		TGF_beta_BMP10	318..421	CDD:381671	50/103 (49%)