Protein Alignment dpp and bmp6

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001106378.1
• Gene: bmp6 / 100127176
• XenbaseID: XB-GENE-479134
• Length: 441
• Species: Xenopus tropicalis
• Alignment Length: 427
• Identity: 125/427 - (29%)
• Similarity: 191/427 - (44%)
• Gaps: 99/427 - (23%)

  Fly   225 EIEKSLLSLFNMKRPPK----IDRSKIIIPEP-------MKKLYAEIMGHE-------------L 265
            |::|.:||:..:...|:    :..|::..|..       |..||..:.|.:             |
 Frog    49 EMQKEILSILGLPHRPRPIHGLSPSQLNQPGKLNSAPLFMLDLYNAMSGQDQGMDLKDWSHRATL 113

  Fly   266 DSVNIPKPGLL------------TKSANTVRSFTH---KDSKIDDRFPHHHRFRLHFDVKSIPAD 315
            .|..:....||            ...|:.|.||.:   .|..:..|..||..::  |::..||..
 Frog   114 HSHQLKVKSLLGSHLGSAQDSAFLSDADMVMSFVNLVEHDKDLSPRLWHHKEYK--FNLSQIPEG 176

  Fly   316 EKLKAAELQLTRDALSQQVVASRSSANRTRYQVLVYDITRVGVRGQREPSYLLLDTKTVRLNSTD 380
            |.:.|||.::.:|.:      ..|..|:| :.:.:|.:  :.....||.:..||||:||..:...
 Frog   177 EAVTAAEFRIYKDCV------LGSFENQT-FLISIYQV--LAEHRNRETNIFLLDTQTVWASDEG 232

  Fly   381 TVSLDVQPAVDRWLASPQRNYG--LLVEVRTVRSL---------KPAPHH--------------H 420
            .:..|:....:.|:.:|:.|:|  |.||.|..|::         :..|:.              |
 Frog   233 WLEFDITATSNLWVMNPRHNFGLQLRVETRDGRNINAKAAGLVGRDGPYDKQPFMVAFFKASEVH 297

  Fly   421 VRLRRSADEAHERWQHKQPLLFTYTDDGRHKARSIRDVSGGEGGGKGGRNKRQPRRPTRRKNHDD 485
            :|..|||....:.....:   :|...| ..:..||.|.:..|                    ...
 Frog   298 LRTTRSATSKRKNQNRNR---YTQAQD-VSRVSSITDYNSSE--------------------LKT 338

  Fly   486 TCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVPK 550
            .||:|.|||.|.|:||.|||:||.||.|.||.|:|.|||..|.|:||||:|||||:.|||..|||
 Frog   339 ACRKHELYVSFQDLGWQDWIIAPKGYAANYCGGECSFPLNAHMNATNHAIVQTLVHLMNPEYVPK 403

  Fly   551 ACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGC 587
            .||.||:|:::::||.:|.|.|:||.|:.|.|..|||
 Frog   404 PCCAPTKLNAISVLYFDDNSNVILKKYRNMVVRACGC 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	59/282 (21%)
		TGFB	487..588	CDD:214556	60/101 (59%)
bmp6	NP_001106378.1	TGFb_propeptide	32..290	CDD:366248	54/251 (22%)
		TGF_beta_BMP6	339..441	CDD:381666	60/102 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1063560at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X157
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920