Protein Alignment dpp and nodal3.2

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001106377.1
• Gene: nodal3.2 / 100127175
• XenbaseID: XB-GENE-6458522
• Length: 401
• Species: Xenopus tropicalis
• Alignment Length: 437
• Identity: 103/437 - (23%)
• Similarity: 168/437 - (38%)
• Gaps: 120/437 - (27%)

  Fly   229 SLLSLF--------NMKRPPKIDRSKII----------------------IPEPMKKLYAEIMG- 262
            :.||||        .|..||.:...|.|                      .|..|.:||..|:.
 Frog     2 AFLSLFLCLVFSSPLMAMPPALQGRKAISPASILKGPSTDNGARDFHGRKFPHFMMQLYQNIISR 66

  Fly   263 HELDSVNIPKPGLLTKSANTVRSFTHKDSKIDDRFPHHHRFRLHFDVKSIPADEKLKAAELQLTR 327
            .:.|..|:..|.|  :.::||:||..|......     :.:.|.||:.||....:||:|||::..
 Frog    67 RDKDLSNLEHPTL--QESDTVQSFIAKSYTTKG-----NHWTLFFDMSSISTSNELKSAELRICL 124

  Fly   328 DALSQQVVASRSSANRTRYQVLVYDITRVGVRGQREPSYL-LLDTKTVRLNSTDTVSLDVQPAVD 391
            .:..:    |.|      ..|.:|.     .:..:|..:: ...||.......|....::...:.
 Frog   125 PSFGK----SHS------VTVEIYH-----TKDDKEKLFMGSFKTKISSALDADCKVFNLTMVLH 174

  Fly   392 RWLASPQR----NY----GLLV-------------EVRTVRSLKPAPHHHVRLRRSADEAHER-- 433
            .:|...:|    .|    |||:             .|..|:..|    |||     :|.:.||
 Frog   175 NYLTKGKRLIKDEYIQAKGLLLRDLEKSATETGAERVDIVKQDK----HHV-----SDFSAERII 230

  Fly   434 -------WQHKQP-------LLFTY---TDDGRHKARSIRDVSGGEGGGKGGRNKRQPRR----- 476
                   ..|.:|       .||..   ..|..:|....|.:.         |||::..|
 Frog   231 LVVFAKEKDHAKPDPPSLGKKLFPSKYGMADSANKVNGFRRLR---------RNKKEKTRMDVGT 286

  Fly   477 --PTRRKNHDDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTL 539
              |...:.....||:..::|||..:||..|||.|..|:||.|...|..||.:..::||::.:::|
 Frog   287 TPPKPVEEIKPKCRKVDMFVDFQKIGWGSWIVYPKAYNAYRCESACAVPLNETDDATNYSYIKSL 351

  Fly   540 VNNMNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCG 586
            :...:..:.....|||.::.|::|||..::. .||::::||.|..||
 Frog   352 LPLSDTDRRECPSCVPVKMRSMSMLYYENED-FVLRHHEEMIVEECG 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	60/283 (21%)
		TGFB	487..588	CDD:214556	35/100 (35%)
nodal3.2	NP_001106377.1	TGFb_propeptide	53..220	CDD:279078	41/192 (21%)
		TGFB	299..399	CDD:214556	35/100 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910