Protein Alignment CG9886 and GLYCTK

DIOPT Version :9

• Sequence 1: NP_001259941.1
• Gene: CG9886 / 33431
• FlyBaseID: FBgn0031428
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_660305.2
• Gene: GLYCTK / 132158
• HGNCID: 24247
• Length: 523
• Species: Homo sapiens
• Alignment Length: 513
• Identity: 201/513 - (39%)
• Similarity: 279/513 - (54%)
• Gaps: 66/513 - (12%)

  Fly     8 EQMRQIFVQAVNAVHPEKVFADFQKFDLRP---QIGENATDISIKLNGERQDISGKTCHIVGFGK 69
            ||.||:|..||.||.|..:.  .:...|.|   |:  ...|.:.:|   ||::     ::|||||
Human    36 EQARQLFESAVGAVLPGPML--HRALSLDPGGRQL--KVRDRNFQL---RQNL-----YLVGFGK 88

  Fly    70 AVLGMANKVQQDLGATSAGGVLSVPVNTLKQFQQPVAPGLV--------VHEGAANNLPDENALK 126
            ||||||...::.||.....||:|||.......::.....::        |.|||.:||||.:||:
Human    89 AVLGMAAAAEELLGQHLVQGVISVPKGIRAAMERAGKQEMLLKPHSRVQVFEGAEDNLPDRDALR 153

  Fly   127 AAREIKQLAEKMTAQDILFVFISGGGSALLPLPRSPLTLEDKRSIADKLMKRGASIQEINAVRIA 191
            ||..|:||||.:||.|:|.|.||||||||||.|..|:|||:|:::...|..|||:|||:|.:|.|
Human   154 AALAIQQLAEGLTADDLLLVLISGGGSALLPAPIPPVTLEEKQTLTRLLAARGATIQELNTIRKA 218

  Fly   192 CSDIKGGRLARLAGQAGLLVTFVLSDIIGDPLELIACGPTIQPEAAASPS-----DILKKHHVWE 251
            .|.:|||.||:.|..| .:|:.:|||::|||:|:||.|||:    |:|.:     .||.::.:..
Human   219 LSQLKGGGLAQAAYPA-QVVSLILSDVVGDPVEVIASGPTV----ASSHNVQDCLHILNRYGLRA 278

  Fly   252 ELSPEIRRVFEQPEEQKNTSLPE---HKV-FVVGSNVIATSTAAHEAERLGYIPCVLSCAVQGDV 312
            .|...::.|..:.:...:.  |.   |.: .::||||:|.:.|..:||.|||...|||.|:||||
Human   279 ALPRSVKTVLSRADSDPHG--PHTCGHVLNVIIGSNVLALAEAQRQAEALGYQAVVLSAAMQGDV 341

  Fly   313 AQVAGDYQRLLH-------------GIQEAKQHGILDPQLREKYAFGERSYPTFR--RALEDHMS 362
            ..:|..|..|.|             .::|       |.||.|..|  |...|..:  .|||....
Human   342 KSMAQFYGLLAHVARTRLTPSMAGASVEE-------DAQLHELAA--ELQIPDLQLEEALETMAW 397

  Fly   363 SKKPLFLICGGEPVIKVSGHGLGGRSQHLALLMSQALHR-DEAMRDCTFLSAGTDGIDGPTDAAG 426
            .:.|:.|:.||||.:::.|.|.|||:|.|||.:...|.| .....|..|||.||||.||||:|||
Human   398 GRGPVCLLAGGEPTVQLQGSGRGGRNQELALRVGAELRRWPLGPIDVLFLSGGTDGQDGPTEAAG 462

  Fly   427 AFGDSSVVESYLGDHTLDELAETLRNCDSYNFYKNLAQGEHHVLTGHTGTNVMDLHFL 484
            |:....:. |......|| :|..|.:.||:.|:..|..|.|.:.||.|||||||.|.|
Human   463 AWVTPELA-SQAAAEGLD-IATFLAHNDSHTFFCCLQGGAHLLHTGMTGTNVMDTHLL 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9886	NP_001259941.1	DUF4147	10..261	CDD:290386	107/266 (40%)
		GckA	12..487	CDD:225254	198/509 (39%)
		MOFRL	367..480	CDD:282951	50/113 (44%)
GLYCTK	NP_660305.2	DUF4147	38..514	CDD:330921	195/505 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156411
Domainoid	1	1.000	156	1.000	Domainoid score	I4176
eggNOG	1	0.900	-	-		E1_COG2379
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14738
Inparanoid	1	1.050	269	1.000	Inparanoid score	I3030
Isobase	1	0.950	-	0	Normalized mean entropy	S5160
OMA	1	1.010	-	-		QHG60856
OrthoDB	1	1.010	-	-		D1371490at2759
OrthoFinder	1	1.000	-	-		FOG0006220
OrthoInspector	1	1.000	-	-		oto90201
orthoMCL	1	0.900	-	-		OOG6_105004
Panther	1	1.100	-	-	LDO	PTHR12227
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2937
SonicParanoid	1	1.000	-	-		X5161
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750