Protein Alignment VGlut and DAL5

DIOPT Version :9

• Sequence 1: NP_001245848.1
• Gene: VGlut / 33427
• FlyBaseID: FBgn0031424
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_012686.3
• Gene: DAL5 / 853617
• SGDID: S000003913
• Length: 543
• Species: Saccharomyces cerevisiae
• Alignment Length: 613
• Identity: 124/613 - (20%)
• Similarity: 190/613 - (30%)
• Gaps: 232/613 - (37%)

  Fly    51 PGGGHAYDDD--DDRPDSPASFEEIERPP-----LR-KIDKYCKAECPCMPARYTIATMACVGFM 107
            |.|...|..|  |:........:|||..|     || ||| ||.  .|.|...|.:..|..:...
Yeast    43 PNGKIVYISDKVDEAMKLAEEAKEIEVTPEEDRKLRWKID-YCM--FPLMCILYAVQFMDKISTS 104

  Fly   108 IA--FGMRCNMSAAKLKGEHNGTVFMNWTVAVESHVDSSFFWGYLVTQIPGGFIASKFPANKIFG 170
            .|  .|:|.::   |:.|:.     .:|       |.|:|::|||...:.        |...||.
Yeast   105 SAAVMGLRTDL---KMHGDQ-----YSW-------VTSAFYFGYLFMNLG--------PVQFIFQ 146

  Fly   171 LSIVSSATLHLFVPFAMTLMHGHVV--------ICVRVLQGLFEGVTYPACHGI--WRFWAPPME 225
            .:...|..|.:|:.....|:..|..        |.:|||.|..|.|..| |..|  .::|....:
Yeast   147 RTSHMSKMLAVFIVIWGMLLALHAAPTVKYPSFIVLRVLLGCAESVVTP-CFTIITAQYWKTEEQ 210

  Fly   226 RSRLAT-LAFSGSYAGVVVGLPLSGLLADAVGYQAPFYAYGVFGIIWYMFWIWLCFENPRKHPAI 289
            .:|::. ...:|          |..:|.:|:       ||||:
Yeast   211 FTRVSIWFGMNG----------LGSILINAI-------AYGVY---------------------- 236

  Fly   290 SIPELKYIEKSLGESAHPTMPSLKTTPWREMMRSMPVYAIIVANFCRSWNFYLLVLFQSSFLKHK 354
             |.:..|..|.                ||.:.....|..|.:......|       ......|.:
Yeast   237 -IHQDSYAIKG----------------WRTLFVITGVITIFIGILIFLW-------IPDDPSKAR 277

  Fly   355 FGFKVEEAGFVGSLPHLIMTTIVPFGGMLADHLRKNGILSTTNVRKLFNCGGFG---------ME 410
            |..|.|:.                   |:...:|.|.             .|||         :|
Yeast   278 FLSKREKL-------------------MVVQRIRSNQ-------------QGFGNHEIKKYQIIE 310

  Fly   411 G-------LFFLFVAHSSTATGAMFALTCGVAFSGFAISGYNVNHLDIAPRYASILMGLSNGIGT 468
            .       |:|||...|:...|.:.:....:..|.|   ||:...        ::||||
Yeast   311 ALKDVRTWLYFLFTVSSNIPNGGISSFMSILLNSDF---GYSSKE--------TLLMGL------ 358

  Fly   469 LAGIIVPYALDGLIQANPTGCWTTVFTLAACVHLVGCTFYGI---FASGELQP-------WAEPP 523
                             |||          .|.||||..:||   :|:.:..|       ||...
Yeast   359 -----------------PTG----------AVELVGCPLFGILAVYAANKKIPFWKYKLSWAIFA 396

  Fly   524 AEEQKVWAPPPGAITNTDPSQ-AGMLGDYMKETSF---------GAPEYTEQSQMQQSTAISYGA 578
            |....:.:...|..||:..:: ||....|:...||         .:..|:::..:.....::|.|
Yeast   397 AVLALIASCMLGFATNSKKARLAGAYLWYISPVSFICVLSNISANSSGYSKKWTVSSINLVAYAA 461

  Fly   579 TGHVANNPFAMASGAPPIAEEDAPPTYG 606
                     |..:|......:.||..:|
Yeast   462 ---------ANLAGPQTFIAKQAPKYHG 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGlut	NP_001245848.1	MFS	98..512	CDD:119392	84/445 (19%)
		MFS_1	101..475	CDD:284993	74/402 (18%)
DAL5	NP_012686.3	MFS_FEN2_like	80..496	CDD:340885	113/576 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	52	1.000	Inparanoid score	I1824
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050