Protein Alignment VGlut and TNA1

DIOPT Version :10

• Sequence 1: NP_608681.2
• Gene: VGlut / 33427
• FlyBaseID: FBgn0031424
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_011776.1
• Gene: TNA1 / 853175
• SGDID: S000003492
• Length: 534
• Species: Saccharomyces cerevisiae
• Alignment Length: 467
• Identity: 103/467 - (22%)
• Similarity: 170/467 - (36%)
• Gaps: 134/467 - (28%)

  Fly    60 DDDRPDSPASFEEIERPPLRKIDKYCKAECPCMPARYTIATMACVGFMIAFGMRCNMSAAKLKGE 124
            |||...||:  ..:|:..|||:|.|.   .|.|...|.::.:.          :.|:..|::.|.
Yeast    69 DDDGIPSPS--HPMEKRVLRKMDIYL---IPLMGMLYFLSNLD----------KSNIGNAEVAGL 118

  Fly   125 HN-----GTVFMNWTVAVESHVDSSFFWGYLVTQIPGGFIASKFPANKIFGLSIVSSATLHLFVP 184
            ..     ||.: |..|.|       ||..|::....|..:.      ||.|..::.|..|..|
Yeast   119 SKDIHLVGTQY-NTCVTV-------FFATYVLFDPIGTNLL------KIMGPPLMMSICLTCF-- 167

  Fly   185 FAMTLMHGHV-----VICVRVLQGLFEGVTYPACHGIWRFWAPPMERSRLA-TLAF-------SG 236
            .|::|....|     :|.||:|.|.|||:.|||   |..:.:....|.:.| ..||       |.
Yeast   168 GAISLGTAWVKNYAQLIVVRLLLGAFEGMIYPA---INMYLSVCYRREQYALRFAFVFSAACLSS 229

  Fly   237 SYAGVVV-GL-PLSGLLAD-----------AVGYQAPFYAYGVFGII---WYM------------ 273
            |:.|::. |. .:||.|.|           ::|: .||||:|:...:   |:.
Yeast   230 SFGGLIAYGCSKISGSLKDWQYIYIVEGCISLGF-VPFYAFGLSKNLEDSWFFNKEEKEYISERY 293

  Fly   274 --------------FWIWLCFENPRK-HPAISIPELKYIEKSLGESAHPTMPSLKTTPWREMMRS 323
                          |.:|...::.:. ..|:::..:......|.......:.|:..|..|..:.:
Yeast   294 KTMNTFDPDEKFEWFQVWQAVKDVKTWASAVALFGIDLTTFGLTVFLPIIITSMGFTNVRAQLMT 358

  Fly   324 MPVYAI--IVANFCRSWNFYLLVLFQSSF-----LKHKFGFKVEEAGFVGSLPHLIMTTIVPFGG 381
            :|:|.:  ||...|..|:.  .:..:|.|     |....|..:    .:||..|.:..    ||
Yeast   359 VPIYFLTAIVFFICAVWSD--RIKLRSPFILGACLTTSIGIAI----VLGSQVHGVRY----FG- 412

  Fly   382 MLADHLRKNGILSTTNVRKLFNCGGFG-------MEGLFFLFVAHSSTATGAMF----------A 429
               .::...||........|:..|..|       ..|:...|.:.|...:|.:|          .
Yeast   413 ---VYILCMGIYVNAACNCLWLSGNTGNYFKRATALGINLFFGSGSGLVSGQIFVAKDKPRYIKG 474

  Fly   430 LTCGVAFSGFAI 441
            |:..:||..|:|
Yeast   475 LSISLAFQVFSI 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGlut	NP_608681.2	MFS_SLC17A6_7_8_VGluT	99..512	CDD:340940	89/428 (21%)
TNA1	NP_011776.1	MFS_FEN2_like	87..490	CDD:340885	95/447 (21%)