DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment VGlut and PHT4;2

DIOPT Version :9

Sequence 1:	NP_001245848.1	Gene:	VGlut / 33427	FlyBaseID:	FBgn0031424	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_001325125.1	Gene:	PHT4;2 / 818384	AraportID:	AT2G38060	Length:	561	Species:	Arabidopsis thaliana

Alignment Length:	435	Identity:	119/435 - (27%)
Similarity:	199/435 - (45%)	Gaps:	57/435 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 YDDDDDRPDSPASFEEIERPPLRKIDKYCKAE---------------CPCMPARYTI----ATMA 102
            |..:.|.....|:.::..:.|.|     |.||               ...||.|..:    |.|.
plant    50 YSSESDGKRRNAAAKKRNQSPER-----CAAEGVLTGGGGSEAIAEVRTMMPERIKVVILTACMM 109

  Fly   103 CVGFMIAFGMRCN-----MSAAKLKGEHNGTVFMNWTVAVESHVDSSFFWGYLVTQIPGGFIASK 162
            |:         ||     ||.|.:.....    :.|:.:....|.|||.|||:.:.:.||.:..:
plant   110 CL---------CNADRVVMSVAVVPLADK----LGWSSSFLGVVQSSFLWGYIFSSVIGGALVDR 161

  Fly   163 FPANKI--FGLSIVSSATLHLFVPFA---MTLMHGHVVICVRVLQGLFEGVTYPACHGIWRFWAP 222
            :...::  :|:::.|.||  |..|:|   .||    .::|||...||.|||..|:...:...|.|
plant   162 YGGKRVLAWGVALWSLAT--LLTPWAAAHSTL----ALLCVRAFFGLAEGVAMPSMTTLLSRWFP 220

  Fly   223 PMERSRLATLAFSGSYAGVVVGLPLSGLLADAVGYQAPFYAYGVFGIIWYMFWIWLCFENPRKHP 287
            ..||:....::.:|.:.|.||||.|:.|:..::|...||..:...|::|...|......||:..|
plant   221 MDERASAVGISMAGFHMGNVVGLLLTPLMLSSIGISGPFILFASLGLLWVSTWSSGVTNNPQDSP 285

  Fly   288 AISIPELKYIEKSLGESAHPTMPSLKTTP-WREMMRSMPVYAIIVANFCRSWNFYLLVLFQSSFL 351
            .|:..||:.|:  .|:...|:..|.|..| .|.::..:|.:|||.||...:|.:::|:.:...:.
plant   286 FITRSELRLIQ--AGKPVQPSTISPKPNPSLRLLLSKLPTWAIIFANVTNNWGYFVLLSWMPVYF 348

  Fly   352 KHKFGFKVEEAGFVGSLPHLIMTTIVPFGGMLADHLRKNGILSTTNVRKLFNCGGFGMEGLFFLF 416
            :..|...:::|.:..:||...|.....:.|..:|.|.:.| .|.|:|||:....||...||..|.
plant   349 QTVFNVNLKQAAWFSALPWATMAISGYYAGAASDFLIRTG-HSVTSVRKIMQSIGFMGPGLSLLC 412

  Fly   417 VAHSSTATGAMFALTCGVAFSGFAISGYNVNHLDIAPRYASILMG 461
            :..:.:.:.|...:|..::.|.|:.:|:.:|..||||:||..|.|
plant   413 LNFAKSPSCAAVFMTIALSLSSFSQAGFLLNMQDIAPQYAGFLHG 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
VGlut	NP_001245848.1	MFS	98..512	CDD:119392	108/379 (28%)
VGlut	NP_001245848.1	MFS_1	101..475	CDD:284993	107/372 (29%)
PHT4;2	NP_001325125.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	253	1.000	Domainoid score	I505
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	284	1.000	Inparanoid score	I857
OMA	1	1.010	-	-		QHG53923
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm1138
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X201
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.080