Protein Alignment VGlut and Slc37a2

DIOPT Version :10

• Sequence 1: NP_608681.2
• Gene: VGlut / 33427
• FlyBaseID: FBgn0031424
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001139432.1
• Gene: Slc37a2 / 56857
• MGIID: 1929693
• Length: 506
• Species: Mus musculus
• Alignment Length: 470
• Identity: 89/470 - (18%)
• Similarity: 172/470 - (36%)
• Gaps: 99/470 - (21%)

  Fly   114 CNMSAAKLKGEH--NGTVFMNWT-------VAVESHVDSSFFWGYLVTQIPGGFIASKFPANKIF 169
            |:.....:...|  |.|.:.:|:       ..:...||::|...|.:.....|....:.|.....
Mouse    54 CSEMVRPVNDTHDLNDTTWCSWSPFDKDDYKELLGAVDNAFLVAYAIGMFISGIFGERLPLRYYL 118

  Fly   170 GLSIVSSATLHLFVPFAMTLMHG-------HVV---ICVRVLQGLFEGVTYPA---CHGIWRFWA 221
            ...:|.|.   ||     |.:.|       |::   :.:::..||.:...:|:   |.|   .|.
Mouse   119 SAGMVLSG---LF-----TSLFGLGYFWNIHMLWYFVLIQICNGLVQTTGWPSVVTCVG---NWF 172

  Fly   222 PPMERSRLATLAFSGSYAGVVVGLPLSGLLAD---AVGYQAPFYAYGVFGIIWYMFWIWL----- 278
            ...:|..:..:..|.:..|.::|..::|:..:   .:.:..|.....:.|:|.::|.|..
Mouse   173 GKGKRGFIMGIWNSHTSVGNILGSLIAGVWVNQHWGLSFIVPGIITAIMGVITFLFLIEYPEDVD 237

  Fly   279 CF---------------ENPRKHPAISIPELKYIEKSLGESAHPTMPSLKTTPWREMMRSMPVYA 328
            |.               |:|...|..|......|..|..:...|...::      ..:.::.:..
Mouse   238 CTPPRHHDDPEKEQDNPEDPVNSPYSSRESNVDIAASSSKEQGPEPEAI------SFLGALRIPG 296

  Fly   329 IIVANFCR------SWNF-YLLVLFQSSFLKHKFGFKVEEAGFVGSLPHLIMTTIVPFGGMLADH 386
            :|..:.|.      |:.| |.|.|:..: :.|   |..:|||        .::|:...||::...
Mouse   297 VIEFSLCLLFAKLVSYTFLYWLPLYIFN-VAH---FSAKEAG--------DLSTLFDVGGIIGGI 349

  Fly   387 LRKNGILST-TNVRKLFNCGGFGMEG-LFFL--FVAHSSTATGAMFALTCGVAFSG------FAI 441
            :.  |::|. ||.|....|....:.. :.||  ::..:...:..:..:.|||..:|      .|:
Mouse   350 MA--GLISDYTNSRATTCCIMLILAAPMMFLYNYIGQNGITSSIVMLIICGVLVNGPYALITTAV 412

  Fly   442 SGYNVNHLDIA--PRYASILMGLSNGIGTLAGIIVPYALDGLIQANPTGCWTTVFTLAACVHLVG 504
            |.....|..:.  .:..|.:..:.:|.|::...:.| .|.|||  :||| |..||.:.....::.
Mouse   413 SADLGTHESLKGNAKALSTVTAIIDGTGSIGAALGP-LLAGLI--SPTG-WNNVFYMLISADVLA 473

  Fly   505 CTFYGIFASGELQPW 519
            |.........|:..|
Mouse   474 CLLLCRLVYKEILAW 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGlut	NP_608681.2	MFS_SLC17A6_7_8_VGluT	99..512	CDD:340940	87/461 (19%)
Slc37a2	NP_001139432.1	MFS_SLC37A1_2	22..484	CDD:340902	87/464 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..266		4/25 (16%)