Protein Alignment VGlut and Slc37a2

DIOPT Version :9

• Sequence 1: NP_001245848.1
• Gene: VGlut / 33427
• FlyBaseID: FBgn0031424
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001178923.1
• Gene: Slc37a2 / 500973
• RGDID: 1564160
• Length: 506
• Species: Rattus norvegicus
• Alignment Length: 470
• Identity: 90/470 - (19%)
• Similarity: 172/470 - (36%)
• Gaps: 99/470 - (21%)

  Fly   114 CNMSAAKLKGEH--NGTVFMNWT-------VAVESHVDSSFFWGYLVTQIPGGFIASKFPANKIF 169
            |:.....:...|  |.|.:.:|:       ..:...||::|...|.:.....|....:.|.....
  Rat    54 CSDIVRPINDTHDLNDTTWCSWSPFDKDDYKELLGAVDNAFLVAYAIGMFISGIFGERLPLRYYL 118

  Fly   170 GLSIVSSATLHLFVPFAMTLMHG-------HVV---ICVRVLQGLFEGVTYPA---CHGIWRFWA 221
            ...:|.|.   ||     |.:.|       |::   :.:::..||.:...:|:   |.|   .|.
  Rat   119 SAGMVLSG---LF-----TSLFGLGYFWNIHMLWYFVLIQICNGLVQTTGWPSVVTCVG---NWF 172

  Fly   222 PPMERSRLATLAFSGSYAGVVVGLPLSGLLAD---AVGYQAPFYAYGVFGIIWYMFWIWL----- 278
            ...:|..:..:..|.:..|.::|..::|:..:   .:.:..|.....|.|:|.::|.|..
  Rat   173 GKGKRGFIMGIWNSHTSVGNILGSLIAGVWVNQHWGLSFIVPGIITAVMGVITFLFLIEYPEDVD 237

  Fly   279 CF---------------ENPRKHPAISIPELKYIEKSLGESAHPTMPSLKTTPWREMMRSMPVYA 328
            |.               |:|...|..|......|..|..:...|...::      ..:.::.:..
  Rat   238 CTPPQHHDDLEKERDNPEDPVNSPYSSRESSVDIAASSSKEQGPEPEAI------SFLGALKIPG 296

  Fly   329 IIVANFCR------SWNF-YLLVLFQSSFLKHKFGFKVEEAGFVGSLPHLIMTTIVPFGGMLADH 386
            :|..:.|.      |:.| |.|.|:..: :.|   |..:|||        .::|:...||::...
  Rat   297 VIEFSLCLLFAKLVSYTFLYWLPLYIFN-VAH---FSAKEAG--------DLSTLFDVGGIIGGI 349

  Fly   387 LRKNGILST-TNVRKLFNCGGFGMEG-LFFL--FVAHSSTATGAMFALTCGVAFSG------FAI 441
            :.  |::|. ||.|....|....:.. :.||  ::..:...:..:..:.|||..:|      .|:
  Rat   350 MA--GLISDYTNGRATTCCVMLILAAPMMFLYNYIGQNGITSSIVMLIICGVLVNGPYALITTAV 412

  Fly   442 SGYNVNHLDIA--PRYASILMGLSNGIGTLAGIIVPYALDGLIQANPTGCWTTVFTLAACVHLVG 504
            |.....|..:.  .:..|.:..:.:|.|::...:.| .|.|||  :||| |..||.:.....::.
  Rat   413 SADLGTHESLKGNAKALSTVTAIIDGTGSIGAALGP-LLAGLI--SPTG-WNNVFYMLISADILA 473

  Fly   505 CTFYGIFASGELQPW 519
            |.........|:..|
  Rat   474 CLLLCRLVYKEILAW 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGlut	NP_001245848.1	MFS	98..512	CDD:119392	88/461 (19%)
		MFS_1	101..475	CDD:284993	76/424 (18%)
Slc37a2	NP_001178923.1	2A0104	77..463	CDD:273319	80/420 (19%)
		MFS	86..481	CDD:119392	83/429 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342622
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930