Protein Alignment VGlut and slc37a4a

DIOPT Version :9

• Sequence 1: NP_001245848.1
• Gene: VGlut / 33427
• FlyBaseID: FBgn0031424
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_999903.1
• Gene: slc37a4a / 406465
• ZFINID: ZDB-GENE-040426-2230
• Length: 429
• Species: Danio rerio
• Alignment Length: 453
• Identity: 103/453 - (22%)
• Similarity: 178/453 - (39%)
• Gaps: 86/453 - (18%)

  Fly    95 RYTIATMACVGFMIAFGMRCNMSAAKLKGEHNGTVFMNWTVAVESHVD--------SSFFWGYLV 151
            |.||.....||:.:.:..|...|            |:..:|..|..:|        ||....|.:
Zfish    10 RATIFLAMFVGYTLYYFNRKTFS------------FVMPSVMQEITLDKDDLGLITSSQSLAYAI 62

  Fly   152 TQIPGGFIASKFPANKIFGLSIVSSATLHLFVPFAMTLMHGHVVICVRVLQGLFEGVTYPACHGI 216
            ::...|.::.:..|..:|.:.:.:...:::....:.::.   |...:..|.||.:|:.:|.|..:
Zfish    63 SKFISGVLSDQMSARWLFSIGLFTVGGINVIFSQSSSVA---VFSGLWFLNGLGQGLGWPPCAKV 124

  Fly   217 WRFWAPPME-RSRLATLAFSGSYAGVVVGLPLSGLLADAVGYQAPFYAYGVFGIIWYMFWIWLCF 280
            .|.|..|.: .:..|.|:.|.:.|| .:|..::.|:|.:..:::.....|:..::..:|    |.
Zfish   125 LRKWFEPSQFGTWWAVLSCSMNLAG-CLGPIIATLMAQSYSWRSTLSISGLTCVVTSIF----CL 184

  Fly   281 ENPRKHPA-ISIPELKY-IEKSLGESA--HPTMPSLKTTP--WREMMRSMPVYAIIVANFCRSWN 339
            ...|..|: :.:|.::. .:|..|.|:  ..|......:|  |...:..:.|:.:..|  ...|.
Zfish   185 IIIRNEPSEVGLPNIEAGAKKGKGGSSKNESTFKEFIFSPYLWLMSLGYLVVFGVKTA--YTDWG 247

  Fly   340 FYLLV--LFQSSFLKHKFGFKVEEAGFVGSLPHLIMTTIVPFGGMLADH-LRKNGILSTTNVRK- 400
            ...|:  ..||:.:...|...:|..|.:|||.          .|.|:|. :.|:|:....|.|.
Zfish   248 QLFLIQDKGQSALMGSSFMSALEIGGLLGSLA----------AGFLSDRAVAKHGLRLYGNPRHG 302

  Fly   401 LFNCGGFGMEGLFFLF----VAHSSTATGAMFALTCGVAFSGFAISG----YNVNHLDIAPRYAS 457
            |......||....:||    .||||.    ::.|..|.|| ||:..|    :.|...:.||
Zfish   303 LLLSMMAGMCVSMYLFRTTVTAHSSN----VWILLLGAAF-GFSSYGPIALFGVLANESAP---- 358

  Fly   458 ILMGLSNGIGTLAGIIVPYA-LDGLIQANPTGC------WTTVFTLA--ACVHLVGCTFYGIF 511
                 ||..||...|:...| :.|.:...|.|.      |.|.|.:|  ||:    .|..|.|
Zfish   359 -----SNYCGTSHAIVALMANVGGFLSGLPFGTVAKHHGWNTAFWVAEIACM----VTTVGYF 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGlut	NP_001245848.1	MFS	98..512	CDD:119392	101/450 (22%)
		MFS_1	101..475	CDD:284993	87/400 (22%)
slc37a4a	NP_999903.1	MFS	14..415	CDD:119392	100/449 (22%)
		2A0104	18..397	CDD:273319	93/424 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582641
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930