Protein Alignment VGlut and slc37a4b

DIOPT Version :9

• Sequence 1: NP_001245848.1
• Gene: VGlut / 33427
• FlyBaseID: FBgn0031424
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001315024.1
• Gene: slc37a4b / 393914
• ZFINID: ZDB-GENE-040426-827
• Length: 453
• Species: Danio rerio
• Alignment Length: 479
• Identity: 95/479 - (19%)
• Similarity: 171/479 - (35%)
• Gaps: 134/479 - (27%)

  Fly   104 VGFMI--------AFGMRCNMSAAKLKGEHNGTVFMNWTVAVESHVDSSFFWGYLVTQIPGGFIA 160
            ||:|:        :|.|...|...:|..|..|.:..:.|:|            |.:::...|.::
Zfish    19 VGYMLYYFNRKTFSFLMPSVMEEIELDKEELGLITSSQTLA------------YAISKFISGVLS 71

  Fly   161 SKFPANKIFGLSIVSSATLHLFVPFAMTLMHGHVVICVRVLQGLFEGVTYPACHGIWRFWAPPME 225
            .:..|..:|.:.:....|:::....:.|:|   :...:..:.|..:|..:|.|..:.|.|..|
Zfish    72 DRISARWLFSIGLFIVGTINIAFSCSSTVM---LFTVLWFVNGFGQGFGWPPCGKVLRKWFEP-- 131

  Fly   226 RSRLAT--------LAFSGSYAGVV-----------VGLPLSGLLADAVGYQAPFYAYGVFGIIW 271
             |:..|        :..:||...::           |.:.:|||:..||..
Zfish   132 -SQFGTWWAILCCSMNLAGSLGPIITTVLVQYYDWRVIMSVSGLICMAVAV-------------- 181

  Fly   272 YMFWIWLCFENPRKHPA-ISIPELK-YIEKSLGESAHPT-MPSLK---TTPWREMMRS--MPVYA 328
                  :|....:..|: :.:|.:: ..:|..|:...|. ..|||   .:|:..::.:  :.|:.
Zfish   182 ------VCLLMVKNEPSDVGLPSIQPGAKKGKGKKGGPNDESSLKDFLLSPYLWVLSAGYLVVFG 240

  Fly   329 IIVANFCRSWN--FYLLVLFQSSFLKHKFGFKVEEAGFVGSLPHLIMTTIVPFGGMLADH-LRKN 390
            :.:|  |..|.  |.:....||:.:...:...:|..||.||:.          .|.|:|. :.:.
Zfish   241 VKIA--CTDWGQLFLMQEKGQSAMMGSSYMSALEVGGFFGSIG----------AGYLSDRAVARQ 293

  Fly   391 GILSTTNVRK---LFNCGGFGM---------------EGLFFLFVAHS-STATGA----MFALTC 432
            |:....|.|.   |....|..:               |...::...|. |..||.    ::.|..
Zfish   294 GLGVYGNPRHGLLLMMMAGMAVSMYLFRVTITPETPEEAPLWVLALHPVSVLTGVSEKELWILIL 358

  Fly   433 GVAFSGFAISG----YNVNHLDIAPRYASILMGLSNGIGTLAGIIVPYA-LDGLIQANPTG---- 488
            |.|| ||:..|    :.|...:.||         ||..||...|:...| :...|...|..
Zfish   359 GAAF-GFSSYGPIALFGVIASESAP---------SNFCGTSHAIVALMANVGAFIAGLPFSTIAK 413

  Fly   489 --CWTTVFTLA--ACVHLVGCTFY 508
              .|.|.|.:|  :|.....|.|:
Zfish   414 RYSWDTAFWVAEVSCAITTVCFFF 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGlut	NP_001245848.1	MFS	98..512	CDD:119392	95/479 (20%)
		MFS_1	101..475	CDD:284993	85/435 (20%)
slc37a4b	NP_001315024.1	UhpC	18..421	CDD:332119	90/461 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582639
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930