Protein Alignment VGlut and Slc37a1

DIOPT Version :9

• Sequence 1: NP_001245848.1
• Gene: VGlut / 33427
• FlyBaseID: FBgn0031424
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001011944.1
• Gene: Slc37a1 / 294321
• RGDID: 1308587
• Length: 537
• Species: Rattus norvegicus
• Alignment Length: 455
• Identity: 103/455 - (22%)
• Similarity: 162/455 - (35%)
• Gaps: 142/455 - (31%)

  Fly   141 VDSSFFWGYLVTQIPGGFIASKFPAN--KIFGLSIVSSATLHLFVPFAMTLMH--GHVVICVRVL 201
            :|.:|...|.:.....|.|..:.|..  ..||: :.|.|...||.......:|  |..|: .:::
  Rat   106 LDYAFLCAYAIGMYLSGIIGERLPIRYYLTFGM-LASGAFTALFGLGYFYNIHSLGFYVV-TQII 168

  Fly   202 QGLFEGVTYPACHGIWRFWAPPMERSRLATLAFSGSYAGVVVGLPLSGLLAD---AVGYQAPFYA 263
            .||.:...:|:.......|.....|..:..:..|.:..|.::|..::|....   .:.:..|...
  Rat   169 NGLVQTTGWPSVVTCLSNWFGKGRRGLIMGIWNSHTSVGNILGSLIAGYWVSTCWGLSFIVPGAI 233

  Fly   264 YGVFGIIWYMFWIWLCFENPR---------KHPAIS----------------------IPELKYI 297
            .|..||:.::|.|    |:|:         .||..|                      .|||:.:
  Rat   234 VGAMGIVCFLFLI----EHPKDIKCSSTLPTHPRASENGINRFRVQKQTTHSEKNGPLDPELQCL 294

  Fly   298 EKSLGES-AHPT----MPSLKTTPWR--EMMRSMPVYAIIVANFCRSWNFYLLVLFQSSFLKHKF 355
            ..|.|:| .||:    :|..:|:...  ....::.:..:|        .|.|.:||.
  Rat   295 LLSDGKSPLHPSHIVVLPGDRTSSMAAISFTGALRIPGVI--------EFSLCLLFA-------- 343

  Fly   356 GFKVEEAGFVGSLPHLIMTTIVPFGGMLADHL--RKNGILSTTNVRKLFNCGG-FG--------- 408
              |:....|:..|| |.:|.:        |||  :|.|.|||     ||:.|| ||
  Rat   344 --KLVSYTFLFWLP-LYITNV--------DHLDAKKAGELST-----LFDVGGIFGGILAGVISD 392

  Fly   409 -ME------GLFFLFVA-----HSSTATGAMFALTCGVAFSGFAISGYNVNHLDIAPRYASI--- 458
             :|      ||..|..|     .||.:...:.|....:..||..:||          .||.|
  Rat   393 RLEKRASTCGLMLLLAAPTLYVFSSVSKMGLEATIAMLLLSGALVSG----------PYALITTA 447

  Fly   459 ----------LMGLSNGIGTLAGII-----VPYALDGLIQA--NPTGCWTTVFTLA----ACVHL 502
                      |.|.|:.:.|:..||     |..||..|:..  :|:| |:.||.:.    ||..|
  Rat   448 VSADLGTHKSLKGNSHALSTVTAIIDGTGSVGAALGPLLAGLISPSG-WSNVFYMLMFADACALL 511

  Fly   503  502
              Rat   512  511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGlut	NP_001245848.1	MFS	98..512	CDD:119392	103/455 (23%)
		MFS_1	101..475	CDD:284993	91/420 (22%)
Slc37a1	NP_001011944.1	MFS_SLC37A1_2	21..520	CDD:340902	103/455 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342619
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930