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Protein Alignment VGlut and SLC17A5

DIOPT Version :9

Sequence 1:	NP_001245848.1	Gene:	VGlut / 33427	FlyBaseID:	FBgn0031424	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_001369562.1	Gene:	SLC17A5 / 26503	HGNCID:	10933	Length:	533	Species:	Homo sapiens

Alignment Length:	434	Identity:	158/434 - (36%)
Similarity:	236/434 - (54%)	Gaps:	36/434 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 EEIERPPLRKIDKYCKAECPCMPARYTIATMACVGFMIAFGMRCNMS------------------ 117
            |..:|.||.......:|...|..|||.:|.:|..||.|.:.:|.|:|
Human    15 ESTDRTPLLPGAPRAEAAPVCCSARYNLAILAFFGFFIVYALRVNLSVALVDMVDSNTTLEDNRT 79

  Fly   118 -------AAKLKGEHNGT-VFMNWTVAVESHVDSSFFWGYLVTQIPGGFIASKFPANKIFGLSIV 174
                   :|.:|..||.| ....|....:..:..|||:||::||||||::|||.....:.|..|:
Human    80 SKACPEHSAPIKVHHNQTGKKYQWDAETQGWILGSFFYGYIITQIPGGYVASKIGGKMLLGFGIL 144

  Fly   175 SSATLHLFVPFAMTLMHGHVVICVRVLQGLFEGVTYPACHGIWRFWAPPMERSRLATLAFSGSYA 239
            .:|.|.||.|.|..|..|.::: :|.|:||.||||:||.|.:|..||||:|||:|.:::::|:..
Human   145 GTAVLTLFTPIAADLGVGPLIV-LRALEGLGEGVTFPAMHAMWSSWAPPLERSKLLSISYAGAQL 208

  Fly   240 GVVVGLPLSGLLADAVGYQAPFYAYGVFGIIWYMFWIWLCFENPRKHPAISIPELKYIEKSLGES 304
            |.|:.|||||::...:.:...||.:|..||.|::.||||..:.|:||..||..|.:||..||...
Human   209 GTVISLPLSGIICYYMNWTYVFYFFGTIGIFWFLLWIWLVSDTPQKHKRISHYEKEYILSSLRNQ 273

  Fly   305 AHPTMPSLKTTPWREMMRSMPVYAIIVANFCRSWNFYLLVLFQSSFLKHKFGFKVEEAGFVGSLP 369
                :.|.|:.||..:::|:|::||:||:|..:|.||.|:....:::|....|.|:|.||:.|||
Human   274 ----LSSQKSVPWVPILKSLPLWAIVVAHFSYNWTFYTLLTLLPTYMKEILRFNVQENGFLSSLP 334

  Fly   370 HLIMTTIVPFGGMLADHLRKNGILSTTNVRKLFNCGGFGMEGLFFLFVAHSSTATG---AMFALT 431
            :|.....:...|..||:||.....||..||::|:.  .||.|.....||.......   |:..||
Human   335 YLGSWLCMILSGQAADNLRAKWNFSTLCVRRIFSL--IGMIGPAVFLVAAGFIGCDYSLAVAFLT 397

  Fly   432 CGVAFSGFAISGYNVNHLDIAPRYASILMGLSNGIGTLAGIIVP 475
            ......||..||:::|||||||.||.||:|::|...|:.|::.|
Human   398 ISTTLGGFCSSGFSINHLDIAPSYAGILLGITNTFATIPGMVGP 441

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.