DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment VGlut and SPBPB10D8.01

DIOPT Version :9

Sequence 1:	NP_001245848.1	Gene:	VGlut / 33427	FlyBaseID:	FBgn0031424	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_595045.1	Gene:	SPBPB10D8.01 / 2541399	PomBaseID:	SPBPB10D8.01	Length:	552	Species:	Schizosaccharomyces pombe

Alignment Length:	437	Identity:	82/437 - (18%)
Similarity:	156/437 - (35%)	Gaps:	122/437 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 YTIATMACVGFMIAFGMRCNMSAAKLKGEHNGTVFMNWTVAVESHVDSS--------FFWGYLVT 152
            :|:..|..:..|:.:..:..:|.:.:.|           :..::|::|:        |:.|:::.
pombe    87 FTVLVMLMILDMMLYIDKATLSYSSILG-----------LFEDTHINSNQYNDINTLFYVGFVIG 140

  Fly   153 QIPGGFIASKFPANKIFGLSIVSSATLHLFVPFAMTLMHGHVVICVRVLQGLFEGVTYPACHGIW 217
            ||||..:..:||.:|....| .:..|:.:|:..|.....|  ::.:|...||.|....|......
pombe   141 QIPGHMLLQRFPVSKFVAAS-TALWTIIIFLHCAAYNFSG--LMALRFFLGLVESSLLPTMEATI 202

  Fly   218 RFWAPPMERSRLATLAFSGSYAGVVVGLPLSGLLADAVGYQ----APFYAYGVF-GIIWYMFWIW 277
            ..:.|..|::.|....:...|.   ..:| :|.:|..|.|.    :|:..:.:. |.|.:...|.
pombe   203 GMFFPHSEQALLQPFFYISCYG---CNIP-AGFIAYGVQYAKNTISPWKLFMIIVGGITFFLTIG 263

  Fly   278 LCF---ENPRKHPAISIPELKYIEKSLGESAHPTMPSLKTTPWREMMRSM--PVYAIIVANFCRS 337
            |.|   :|......::..|..|....:..|.|..:.| ||....:::.::  ||          :
pombe   264 LFFYYPDNTSTARFLTKKERLYTVDRVRRSNHSGIES-KTFKKYQVIEALKDPV----------T 317

  Fly   338 WNFYLLVLFQSSFLKHKFGFKVEEAGFVGSLPHLIMTTIVPFGGMLADHL--RKNGILSTTNVRK 400
            |.|                                  |...|...|:::|  ::|.:.::.||..
pombe   318 WLF----------------------------------TFHVFCNQLSNNLAYQQNLLFTSLNVSD 348

  Fly   401 L-----------FNCGGFGMEGLFFLFVAHSSTATGAMFALTCGVAFSGFAISGYNVNHLDIAPR 454
            |           :||....:.......:.:.|...||::.:.                  .||..
pombe   349 LNSTLVGVASAGYNCVSAIIATYMMSVIKNQSAFHGAIWYIP------------------SIAGG 395

  Fly   455 YASILMGLSNGIGTLAGIIVP--YALDGLIQANPTGCWTTVFTLAAC 499
            .|.:.|...:.||.||.||:.  :.:..:|...    |||    |:|
pombe   396 IACVAMSWDHKIGELAAIIIASNFGIPFIISLG----WTT----ASC 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
VGlut	NP_001245848.1	MFS	98..512	CDD:119392	81/435 (19%)
VGlut	NP_001245848.1	MFS_1	101..475	CDD:284993	75/404 (19%)
SPBPB10D8.01	NP_595045.1	MFS	90..492	CDD:119392	81/434 (19%)
SPBPB10D8.01	NP_595045.1	2A0114	101..497	CDD:273326	79/423 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050