DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment VGlut and slc-17.8

DIOPT Version :9

Sequence 1:NP_001245848.1 Gene:VGlut / 33427 FlyBaseID:FBgn0031424 Length:632 Species:Drosophila melanogaster
Sequence 2:NP_001023848.1 Gene:slc-17.8 / 179234 WormBaseID:WBGene00017798 Length:527 Species:Caenorhabditis elegans


Alignment Length:504 Identity:120/504 - (23%)
Similarity:212/504 - (42%) Gaps:46/504 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    57 YDDDDDRPD----SPASFEEI-------ERPPLRKIDKYCKAECPCMPA-RYTIATMACVGFMIA 109
            |||....||    |.:|...|       :||...:          ..|: |:..:.|.|..|...
 Worm    13 YDDAAKSPDQLLRSMSSVHPISDGIPSQQRPLTYR----------WFPSWRFMTSIMLCFCFGCV 67

  Fly   110 FGMRCNM---------SAAKLKGE---HNGTVFMNWTVAVESHVDSSFFWGYLVTQIPGGFIASK 162
            ..|..||         |:|....|   .|....::|:...:.::.|:|..|.||....|| :|.|
 Worm    68 HLMNSNMGMAIVCMVNSSATYDNETYPENAAPLLDWSSDEQGYIFSAFNAGLLVMLFTGG-MADK 131

  Fly   163 FPANKIFGLSIVSSATLHLFVPFAMTLMHGHVVICVRVLQGLFEGVTYPACHGIWRFWAPPMERS 227
            |.|..:..:|:..::..:..:|: |..:..:..|..|.|.|..:.:..||.:.:...|.|..|||
 Worm   132 FNAKYMILVSVAIASLANFTLPW-MAPISVYWAIFSRFLVGFADALLQPAMNSLITRWFPTSERS 195

  Fly   228 RLATLAFSGSYAGVVVGLPLSGLLADAV----GYQAPFYAYGVFGIIWYMFWIWLCFENPRKHPA 288
            ....||..|...|.::.:|.:|.|....    |:.:.||..|..|:::...:|:|..:.|.|...
 Worm   196 YALGLATGGRQIGTLIIIPAAGALCSQTEIFGGWPSIFYLSGFIGVLFIFSYIFLGADKPSKQSC 260

  Fly   289 ISIPELKYIEKSLGESAHPTMPSLKTTPWREMMRSMPVYAIIVANFCRSWNFYLLVLFQSSFLKH 353
            ||..|||:|..|..........:.:..||:.:::|..|:|.:::..|..:....|::|..|:|..
 Worm   261 ISDNELKFITISNQSEDVGKKRTERKVPWKNILKSGAVWASVISLVCHEFPLMTLIMFLPSYLHD 325

  Fly   354 KFGFKVEEAGFVGSLPHLIMTTIVPFGGMLADHLRKNGILSTTNVRKLFN-CGGFGMEGLFFL-- 415
            ...:...|.|.:.:||.:.:.........|...|:||.......:.|:.| .|..|: |:|.|  
 Worm   326 VHHYHSTENGILSALPTVSLWFAKIGSSYLNTWLQKNTTWKKDTICKVLNSIGSIGL-GVFLLAA 389

  Fly   416 -FVAHSSTATGAMFALTCGVAFSGFAISGYNVNHLDIAPRYASILMGLSNGIGTLAGIIVPYALD 479
             |:.:.......:| |...:|.:|....|..:..:.:||.|:..:.|.:.....::|||.|....
 Worm   390 TFLDNEHAWMAVLF-LCLSMASAGLHTPGCQLALVSVAPAYSGAVTGFTFFFVAVSGIIHPIITK 453

  Fly   480 GLIQANPTGCWTTVFTLAACVHLVGCTFYGIFASGELQPWAEPPAEEQK 528
            .:::......|..||.::..:.:.....:.::.|.|:|.||:..|..|:
 Worm   454 MIVKDRTAAEWNLVFYISTVIAIFPIIIFNVWGSTEVQWWAKSKASMQQ 502

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
VGlutNP_001245848.1 MFS 98..512 CDD:119392 101/433 (23%)
MFS_1 101..475 CDD:284993 97/393 (25%)
slc-17.8NP_001023848.1 MFS_SLC17 57..486 CDD:340876 101/432 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D497052at2759
OrthoFinder 1 1.000 - - FOG0000034
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.920

Return to query results.
Submit another query.