Protein Alignment VGlut and C01B4.7

DIOPT Version :10

• Sequence 1: NP_608681.2
• Gene: VGlut / 33427
• FlyBaseID: FBgn0031424
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_503683.1
• Gene: C01B4.7 / 178722
• WormBaseID: WBGene00015271
• Length: 475
• Species: Caenorhabditis elegans
• Alignment Length: 523
• Identity: 109/523 - (20%)
• Similarity: 195/523 - (37%)
• Gaps: 135/523 - (25%)

  Fly    36 GGYEEME---GGDREGRGPGGGHAYDDDDDRPDSPASFEEIERPPLRKIDKY----------CKA 87
            |.||.::   |||                         .:|...|.|||..:          ...
 Worm     5 GDYEMVKVVGGGD-------------------------SDIFETPQRKISNFVFWNQTRVFILIL 44

  Fly    88 ECPCMP-----ARYTIATMACVGFMIAFGMRCNMSAAKLKGEHNGTVFMNWTVAVESHVDSSFFW 147
            ...||.     ::....|:.|:..:|......|::..            :|   :|...:.|..:
 Worm    45 SLTCMTLTQINSQIFTFTVICMDDLIVEQQTSNLTEP------------HW---IEGTTEKSILF 94

  Fly   148 -----GYLVTQIPGGFIASKFPANKIFGLSIVSSATLHLFVPFAMTLMHGHVVICVRVLQGLFEG 207
                 |.||..||...|.:............:.|.....|.|.|:|.....||.| |||||:...
 Worm    95 SATAIGALVALIPSVPILNSLGVRLTLSFCGLCSTLGTFFTPLAVTYSFYLVVFC-RVLQGIGIS 158

  Fly   208 VTYPACHGIWRFWAPPMERSR-LATLAFSGSYAGVVVGLPLSGLLAD-AVGYQAPFYAYGV---- 266
            |.......|..:|:|..|.|. ||.|:.:..::.|:. :|:||:|.| :.|:::.:|.:||
 Worm   159 VILTVLGVIPSYWSPKTEYSTYLAILSCAWQFSNVIF-MPISGILCDSSFGWRSIYYVFGVATGF 222

  Fly   267 FGIIWYMFWIWLCFENPRKHPAISIPELKYIEKSLGE--SAHPTMPSLKTTPWREMMRSMPVYAI 329
            |..:::||:.    :.|..|..:|       ||.||:  ...|.....:..|:.::.....|.:.
 Worm   223 FYFVFFMFYT----DIPGIHKNVS-------EKELGQIVEGKPEHTVREAVPYWKICTDRCVLSA 276

  Fly   330 IVANFCRSWNFYLLVLFQSSFLKHKFGFKVEEAGFVGSLPHLIMTTIVPFG-GMLADHLRKNGIL 393
            .|:....:..|..|:|:..::|:....|.|...|::.:||: .:..|..|| |.::|.      :
 Worm   277 WVSFLGGNLGFITLLLYGPTYLREVLQFDVRSTGYINALPY-ALCAIYKFGAGKISDR------V 334

  Fly   394 STTNVRKLFNCGGF----GMEGLFFLFVAHSSTATGAMFALTCGVAFSG---------------- 438
            :..:.:.::....|    |: |:.::.:|.:|....|..|....|..||
 Worm   335 TFASDKAIYTFWLFSSIIGL-GIGYIIMAWTSDRNVAFVAFAFAVVTSGLIIMACVKCLAMRCQQ 398

  Fly   439 ---FAISGYNVNHLDIAPRYASILMGLSNGIGTLAGIIVPYALDGLIQANPTGCWTTVFTLAACV 500
               ||:|.  ::.|....::.|.|     |:    ||:.|        .|....|:.:|.:...:
 Worm   399 HCHFAVSA--ISFLSYCVQFISPL-----GV----GILCP--------DNTPDQWSRLFIIITLI 444

  Fly   501 HLV 503
            .::
 Worm   445 MII 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGlut	NP_608681.2	MFS_SLC17A6_7_8_VGluT	99..512	CDD:340940	96/442 (22%)
C01B4.7	NP_503683.1	MFS	89..>332	CDD:475125	66/256 (26%)