Protein Alignment VGlut and Y4C6B.3

DIOPT Version :10

• Sequence 1: NP_608681.2
• Gene: VGlut / 33427
• FlyBaseID: FBgn0031424
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001293768.1
• Gene: Y4C6B.3 / 177313
• WormBaseID: WBGene00021157
• Length: 459
• Species: Caenorhabditis elegans
• Alignment Length: 431
• Identity: 98/431 - (22%)
• Similarity: 184/431 - (42%)
• Gaps: 71/431 - (16%)

  Fly   126 NGTV--FMNWTVAVESHVDSSFFWGYLVTQIPGGFIASKFPANKI----------FGLSIVSSAT 178
            |||:  ..::|...:.|:    .|.     :..|.|...||.|.:          |...::|:.|
 Worm    49 NGTIRSMYDYTPTEKKHI----LWA-----VSFGTIVGIFPINMLYVQCGARLAFFSAGLLSAMT 104

  Fly   179 LHLFVPFAMTLMHGHVVICVRVLQGLFEGVTYPACHGIWRFWAPPMERS-RLATLAFSGSYAGVV 242
            . .|.|:|.: .....::.:|.|||:.....:.|...|...|||..|.: .:|||....:.:.::
 Worm   105 T-AFTPWAAS-QSMWFLVALRFLQGVAYSADFAAIGIIISKWAPLDETAVFIATLTSFTAISSII 167

  Fly   243 VGLPLSGLLADA-VGYQAPFYAYGVFGIIWYMFWIWLCFENPRKHPAISIPELKYIEKSLGESAH 306
            .. .:||::.:: :|::..||.:....:|.::.|..:...:|..|.::|..||..|:|:..: ||
 Worm   168 TN-GVSGVICESHLGWRWSFYLHAAACLIVFLTWGLVYKNDPSLHKSVSAKELGKIQKNKSD-AH 230

  Fly   307 PTMPSLKTTPWREMMRSMPVYAIIVANFCRSWNFYLLVLFQSSFLKHKFGFKVEEAGF-VGSLPH 370
              |......|:|::..|..|..:.:..|.......|:..:...:.::...|.::..|| :|
 Worm   231 --MKDSMQIPYRKIFTSPVVITVWLCAFTELSTLILIATYAPIYFRNVLKFDIKMIGFYLG---- 289

  Fly   371 LIMTTIVPFG---GMLADHLRKNGILSTTNVRKLFNCGGFGMEGLFFLFVA-----HSSTATGAM 427
            ||:...:||.   .:|:|   |...:|..:...:||....|..|:.|:...     |:.:|...:
 Worm   290 LILAIHLPFRFVCALLSD---KTRCISEMSKIHIFNTLSVGFVGISFIAFGQIPHEHNLSAVICL 351

  Fly   428 FALTCGVAFS--GFAISGYNVNHLDIAPRYASILMG---LSNGIGTLAG--IIVPYALDGLIQAN 485
            ..|.|..:||  ||    |....|. |.:::||::.   .:..|...:|  ::..:..|   ::|
 Worm   352 GVLECFTSFSSGGF----YKCGTLH-ARQFSSIVISAIQFTKCIALFSGPALVAFFVTD---ESN 408

  Fly   486 PTGCWTTVFTLAACVHLVGCTFYG-----IFASGELQPWAE 521
            .|. |:.||     :.|.|.||:.     |:.:.:...|.|
 Worm   409 QTQ-WSHVF-----MTLAGFTFFANILSYIYFTDQPAEWTE 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGlut	NP_608681.2	MFS_SLC17A6_7_8_VGluT	99..512	CDD:340940	96/420 (23%)
Y4C6B.3	NP_001293768.1	MFS	15..433	CDD:475125	95/419 (23%)