Protein Alignment VGlut and slc-17.2

DIOPT Version :10

• Sequence 1: NP_608681.2
• Gene: VGlut / 33427
• FlyBaseID: FBgn0031424
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_499065.1
• Gene: slc-17.2 / 176317
• WormBaseID: WBGene00008000
• Length: 493
• Species: Caenorhabditis elegans
• Alignment Length: 475
• Identity: 159/475 - (33%)
• Similarity: 239/475 - (50%)
• Gaps: 45/475 - (9%)

  Fly    95 RYTIATMACVGFMIAFGMRCNMSAAKL-----------------------KGEHNGTVF--MNWT 134
            |:.::.:...|.::.:.||.|||.|.:                       ..|.|.:|.  .:|.
 Worm    15 RFALSLVMFFGCLVTYMMRTNMSFAVVCMVNENKTDTGVEKVSRCGKEMTPVESNSSVIGEFDWD 79

  Fly   135 VAVESHVDSSFFWGYLVTQIPGGFIASKFPANKIFGLSIVSSATLHLFVPFAMTLMHGHVVICVR 199
            ......|.||||:||:.:||.||.:||::...::..::|:.||.|.|..|.|..... :.:..:|
 Worm    80 KQTTGMVLSSFFYGYIGSQIIGGHLASRYGGKRVVFVTILGSALLTLLNPVAARTSE-YALAILR 143

  Fly   200 VLQGLFEGVTYPACHGIWRFWAPPMERSRLATLAFSGSYAGVVVGLPLSGLLAD---AVGYQAPF 261
            ...|..:|.|:||.|.:|..|.||:|.|.|..:.::|:..|.|:.|||||.|.:   ..|:.:.|
 Worm   144 AAIGFLQGATFPAMHTMWSVWGPPLELSVLTGVTYAGAQIGNVIVLPLSGFLCEYGFDGGWPSIF 208

  Fly   262 YAYGVFGIIWYMFWIWLCFENPRKHPAISIPELKYI----EKSLGESAHPTMPSLKTTPWREMMR 322
            |..||||::|...|.::..:.|..||.|:..|.:||    |.|:|:.. ..:||   |||.:::.
 Worm   209 YIIGVFGVLWTAVWWYVSSDKPATHPRITPEEKQYIVTAVEASMGKDT-GKVPS---TPWIKILT 269

  Fly   323 SMPVYAIIVANFCRSWNFYLLVLFQSSFLKHKFGFKVEEAGFVGSLPHLIMTTIVPFGGMLADHL 387
            |..|:|....:|...|..|.:::...||||...|..:...|.|.|:|::.....:..||:|||.|
 Worm   270 SPAVWACWAGHFAGDWGAYTMLVSLPSFLKDVLGLNLSSLGAVASIPYIAYFLAINAGGVLADTL 334

  Fly   388 RKNGILSTTNVRKLFNCGGFGMEGLFFLFVAHSSTATG----AMFALTCGVAFSGFAISGYNVNH 448
            |..|||||.|.|:.........:|:|  .||......|    .:..:|||:|.||...:|:.||:
 Worm   335 RSKGILSTLNTRRAAMLVALIGQGIF--LVASGYCGCGQDVLVIIFITCGMAISGLQYAGFVVNY 397

  Fly   449 LDIAPRYASILMGLSNGIGTLAGIIVPYALDGLIQANPT-GCWTTVFTLAACVHLVGCTFYGIFA 512
            |:|||.::..:||..|.|..|||||.| |:...:..|.| ..|..|..|.|.:..:|...:.|||
 Worm   398 LEIAPPFSGTVMGTGNTISALAGIISP-AVSSYLTPNGTQEEWQMVLWLTAGILTIGALLFSIFA 461

  Fly   513 SGELQPWAEPPAEEQKVWAP 532
            |||:||||:..|||....||
 Worm   462 SGEVQPWAKLTAEEGHEMAP 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGlut	NP_608681.2	MFS_SLC17A6_7_8_VGluT	99..512	CDD:340940	144/449 (32%)
slc-17.2	NP_499065.1	MFS_SLC17	19..461	CDD:340876	144/449 (32%)