Protein Alignment VGlut and vnut-1

DIOPT Version :10

• Sequence 1: NP_608681.2
• Gene: VGlut / 33427
• FlyBaseID: FBgn0031424
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_497007.1
• Gene: vnut-1 / 175106
• WormBaseID: WBGene00010758
• Length: 445
• Species: Caenorhabditis elegans
• Alignment Length: 473
• Identity: 121/473 - (25%)
• Similarity: 203/473 - (42%)
• Gaps: 59/473 - (12%)

  Fly    67 PASFEEIERPPLRKIDKYCKAECPCMPARYTIATMACVGFMIAFGMRCNM--SAAKLKGEHNGTV 129
            |..:|    |||.||  :.:||     :|....||.. |..:.:..|.::  |||.:..|
 Worm     5 PGEYE----PPLGKI--WTRAE-----SRMWTITMFS-GTCVLYASRASLPISAAAVAKE----- 52

  Fly   130 FMNWTVAVESHVDSSFFWGYLVTQIPGGFIASKFPANKIFGLSIVSSATLHLFVP----FAMTLM 190
             ..|.......|.|.|||||.:||:..|.||.|:.|.||...|.::...|..|.|    ||....
 Worm    53 -FAWNKTDSGTVLSCFFWGYALTQVFAGRIADKYGAEKILPYSSLAWTMLTFFTPHLFDFAYWTN 116

  Fly   191 HGHVV-ICVRVLQGLFEGVTYPACHGIWRFWAPPMERSRLATLAFSGSYAGVVVGLPLSGLLADA 254
            :..|| :.||:|.|:.:....|:...|........::.|:..:..:||:.|.|:...:..:|.:.
 Worm   117 YPLVVLLAVRILTGVCQAFHIPSLASIVSKHLAAADKGRVFGIVLAGSHWGTVLAGAIGSILIEW 181

  Fly   255 VGYQAPFYAYGVFGIIWYMFWIWLC--FENP--RKHPAISIPELKYIEKSLGESAHPTMPS---- 311
            :|::|.|...|:..:||...:.|:.  .:.|  |..|   :|:    |:.|.:..|.|:.|
 Worm   182 IGWRALFQFVGIISLIWCWVFRWVLDRAKGPGGRSSP---LPD----EEVLLDKKHDTIESHLAA 239

  Fly   312 ---LKTTPWREMMRSMPVYAIIVANFCRSWNFYLLVLFQSSFLKHKF----GFKVEEAGFVGSLP 369
               ..:.||..:.|....:|..||.:....::.:|..:..|:....|    ||..   ..|.||.
 Worm   240 TSPCPSVPWGTLFRHPAFWAAAVAQYTGGNSYSILFNWLPSYFHETFPTAKGFVY---NVVPSLA 301

  Fly   370 HLIMTTIVPFGGMLADHLRKNGILSTTNVRKLFNCGGFGMEGLFF--LFVAHSSTATGAMFALTC 432
            .::.:.:.|   ::|......| .:.|..|||..  |..:.|:.|  :.|..:|:...::...|.
 Worm   302 IVVTSLVAP---VMASRALSEG-KTVTYTRKLME--GASLLGIAFCLMLVPMTSSFWISLIIFTM 360

  Fly   433 GVAFSGFAISGYNVNHLDIAPRYASILMGLSNGIGTLAGIIVPYALDGLIQANPTGCWTTVFTLA 497
            .:|..|....|.:||..|.||.:|..:.|:.|..|.:.|.:..|....:::|.... |:.||.:.
 Worm   361 AMAARGLHHGGVSVNPHDFAPNHAGSVFGVFNACGAITGFVGVYIAGHILEATNNN-WSYVFVVT 424

  Fly   498 ACVHLVGCTFYGIFASGE 515
            |...:||...|.:..:|:
 Worm   425 AAQCVVGAMVYTLLGTGQ 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGlut	NP_608681.2	MFS_SLC17A6_7_8_VGluT	99..512	CDD:340940	110/436 (25%)
vnut-1	NP_497007.1	MFS_SLC17A9_like	25..439	CDD:340938	110/437 (25%)