Protein Alignment VGlut and T01H3.3

DIOPT Version :9

• Sequence 1: NP_001245848.1
• Gene: VGlut / 33427
• FlyBaseID: FBgn0031424
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_495657.2
• Gene: T01H3.3 / 174270
• WormBaseID: WBGene00011349
• Length: 616
• Species: Caenorhabditis elegans
• Alignment Length: 566
• Identity: 115/566 - (20%)
• Similarity: 194/566 - (34%)
• Gaps: 99/566 - (17%)

  Fly    30 SYHG-GHGGYEEMEGGDREGRGPGGGHAYD---DDDDRP-----DSPASFEEIERPPLRKIDKYC 85
            |.|| .:.||..::....|.|.|.....:|   :|:..|     :.||.....|.|..|:.:|..
 Worm    59 SLHGSSYKGYNRLKRELSESRIPSKVVRFDESTEDEGHPILPPTEKPAPVITTETPTTRETEKPV 123

  Fly    86 KAECPCMPARYTIATMACVGFMI-------AFGMRCNMSAAKLKGEHNG-------TVFMNWTVA 136
            .......|...|:..:......:       ........:..||:...:|       .:|.|.:..
 Worm   124 PIFITNRPETTTVRAVRTTTKKVETTTSDDVVAREVERTLKKLRDAEDGKSESIPEQLFENVSNE 188

  Fly   137 VESHVDSSFFWGYLVTQ-----IPGGFIA----SKFPANKIFGLSIVSSATLHLFVPFAMTLMHG 192
            ....:......|.|...     |.|.|:.    .||...|:|.:.:|.|..|.|.  |.......
 Worm   189 PTETLPLRLQRGLLFAASGLGVIFGSFVTINLIKKFGVRKVFSICMVQSTILILL--FLYVQKRS 251

  Fly   193 HV-VICVRVLQGLFEGVTYPACHGIWRFWAPPMERSRLATLAFSGSYAGVVVGLPLSGLL-ADAV 255
            :: ::..|.|.|......:|....:...|.|..|:....|..|.....|.||..|::... |..:
 Worm   252 YIFLLLTRFLLGFSFSSVFPVMGNLLIQWGPLKEQLIFITSMFMFLSIGPVVSWPIAHYFHALEI 316

  Fly   256 GYQAPFYAYGVFGIIWYMFWIWLCF--ENPRKHPAISIPELKYI----------EKSLGESAHPT 308
            ...:.:|..  .|.:.::..||..|  :.|:.||.:|..||..|          .::|.::
 Worm   317 SLDSVYYIQ--CGTLAFLTLIWSIFYRDRPQDHPWVSGVELNKIVAGKVNELRSNRALADA---- 375

  Fly   309 MPSLKTTPWREMMRSMPVYAIIVANFCRSWNFYLLVLFQSSFLKHKFG----FKVEEAGFVGSLP 369
                    :..:.||:..::|..:.|    ..:.:..|.|.:|.....    |.||..|...|.|
 Worm   376 --------YTSLFRSLSAWSIWTSAF----GLFSVTAFFSIYLPSLLASPDVFVVEGLGIHSSFP 428

  Fly   370 -HLIMTTIVPFGGMLADHLRKNGIL--STTNVRKLFNCGGFGMEGLFFL---FVAHSSTATGAMF 428
             .|:..:.:.|..:        .:|  .:|.:.::.|...|.:..:..:   .||...|..|...
 Worm   429 FQLLPLSCIIFSSL--------NVLFKPSTKIVRILNFTAFAIGAILMIAIVLVASLQTKAGLFS 485

  Fly   429 ALTCGVAFSGFAISGYNVNHLDIAPR-YASILMGLSNGIGTLAGIIVPYALDGLIQANPTGCWTT 492
            .|...:...|.||....|..|.:..| :|..::.:......||..|:|..:...:..|....|..
 Worm   486 LLLISMLPFGLAIVAGFVRSLTVVGRVFAEQIVAMCAVPFGLAFSILPMVVTYSVTENKLAEWMK 550

  Fly   493 V-----FTLAACVHLVGCTFYGIFASGELQPWA----EPPAEEQKV 529
            |     |.|:|    |...| .:|..|:...||    :|.|...|:
 Worm   551 VTMFLFFVLSA----VAIEF-AVFGRGKSASWAASSWDPLAASTKM 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGlut	NP_001245848.1	MFS	98..512	CDD:119392	89/466 (19%)
		MFS_1	101..475	CDD:284993	80/421 (19%)
T01H3.3	NP_495657.2	MFS	200..564	CDD:119392	83/395 (21%)
		MFS_1	200..508	CDD:284993	70/335 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910