Protein Alignment VGlut and Slc17a7

DIOPT Version :10

• Sequence 1: NP_608681.2
• Gene: VGlut / 33427
• FlyBaseID: FBgn0031424
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: XP_038966881.1
• Gene: Slc17a7 / 116638
• RGDID: 620101
• Length: 585
• Species: Rattus norvegicus
• Alignment Length: 639
• Identity: 275/639 - (43%)
• Similarity: 353/639 - (55%)
• Gaps: 118/639 - (18%)

  Fly     7 FKEKATGVFGGLKPNMEKFEISQSYHGGHGGYEEMEGGDREGRGPGGGHAYDDDDDRPDSPASFE 71
            |::.|....|.|...:||.:         .|.|.:| ...:|| |...|..|
  Rat     8 FRKLAGRALGRLHRLLEKRQ---------EGAETLE-LSADGR-PVTTHTRD------------- 48

  Fly    72 EIERPPLRKIDKYCKAECPC--MPARYTIATMACVGFMIAFGMRCNMSAAKLKGEHNGTVF---- 130
                ||:        .:|.|  :|.||.||.|:.:||.|:||:|||:..|.:...:|.|..
  Rat    49 ----PPV--------VDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTTHRGGH 101

  Fly   131 --------------------------------MNWTVAVESHVDSSFFWGYLVTQIPGGFIASKF 163
                                            .||.......:..||||||:|||||||||..||
  Rat   102 VVVQTPYRSVHKQEAVTPTVGDIQGGDTEKAQFNWDPETVGLIHGSFFWGYIVTQIPGGFICQKF 166

  Fly   164 PANKIFGLSIVSSATLHLFVPFAMTLMHGHVVICVRVLQGLFEGVTYPACHGIWRFWAPPMERSR 228
            .||::||.:||:::||::.:|.|..:.:| .||.||:||||.||||||||||||..||||:||||
  Rat   167 AANRVFGFAIVATSTLNMLIPSAARVHYG-CVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSR 230

  Fly   229 LATLAFSGSYAGVVVGLPLSGLLADAVGYQAPFYAYGVFGIIWYMFWIWLCFENPRKHPAISIPE 293
            |||.||.|||||.||.:||:|:|....|:.:.||.||.|||.||:||:.:.:|:|..||:||..|
  Rat   231 LATTAFCGSYAGAVVAMPLAGVLVQYSGWSSVFYVYGSFGIFWYLFWLLVSYESPALHPSISEEE 295

  Fly   294 LKYIEKSLGESAHPTMPSLK-TTPWREMMRSMPVYAIIVANFCRSWNFYLLVLFQSSFLKHKFGF 357
            .||||.::||||....|..| .||||....||||||||||||||||.||||::.|.::.:..|||
  Rat   296 RKYIEDAIGESAKLMNPVTKFNTPWRRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGF 360

  Fly   358 KVEEAGFVGSLPHLIMTTIVPFGGMLADHLRKNGILSTTNVRKLFNCGGFGMEGLFFLFVAHSST 422
            ::.:.|.|.:||||:||.|||.||.:||.||...|:||||||||.||||||||....|.|.:|.:
  Rat   361 EISKVGLVSALPHLVMTIIVPIGGQIADFLRSRHIMSTTNVRKLMNCGGFGMEATLLLVVGYSHS 425

  Fly   423 ATGAMFALTCGVAFSGFAISGYNVNHLDIAPRYASILMGLSNGIGTLAGIIVPYALDGLIQANPT 487
            ...|:..|...|.||||||||:|||||||||||||||||:|||:|||:|::.|..:..:.:....
  Rat   426 KGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKHKTR 490

  Fly   488 GCWTTVFTLAACVHLVGCTFYGIFASGELQPWAEPPAEEQKVWAPPPGAITNTDPSQAGMLGDYM 552
            ..|..||.:|:.||..|..|||:|||||.||||||  ||.             ...:.|.:|...
  Rat   491 EEWQYVFLIASLVHYGGVIFYGVFASGEKQPWAEP--EEM-------------SEEKCGFVGHDQ 540

  Fly   553 KETSFGAPEYTEQSQMQQSTAISYGATGHVANNPFAMASGAPPIAEEDAPPTYG 606
            ...|       ::|:|:....                ..||||.    .||:||
  Rat   541 LAGS-------DESEMEDEVE----------------PPGAPPA----PPPSYG 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGlut	NP_608681.2	MFS_SLC17A6_7_8_VGluT	99..512	CDD:340940	227/449 (51%)
Slc17a7	XP_038966881.1	MFS_SLC17A6_7_8_VGluT	66..515	CDD:340940	227/449 (51%)