Protein Alignment VGlut and Slc17a3

DIOPT Version :9

• Sequence 1: NP_001245848.1
• Gene: VGlut / 33427
• FlyBaseID: FBgn0031424
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_598830.2
• Gene: Slc17a3 / 105355
• MGIID: 2389216
• Length: 498
• Species: Mus musculus
• Alignment Length: 492
• Identity: 137/492 - (27%)
• Similarity: 229/492 - (46%)
• Gaps: 56/492 - (11%)

  Fly    74 ERPPLRKIDKYCKAECPCMPARYTIA--------TMACVGFMIAFGM-----------RCNMSAA 119
            ::.|..|:...|.       .||.||        |:.....:|:..|           ..|.|..
Mouse    24 KKTPALKVPSLCS-------MRYGIAFVTHFCNFTLMAQNSIISITMVAMVNNTDHPPHLNSSTE 81

  Fly   120 KLKG-----EHNGTVFM-------NWTVAVESHVDSSFFWGYLVTQIPGGFIASKFPANKIFGLS 172
            :|..     :|..:..:       ||:...:..:.||..:|.::.|.|||::|.|....|:.|::
Mouse    82 QLPAGLSGDQHEASKHLPIKAPVYNWSPQTQGIIFSSVQYGMILMQGPGGYLAGKIGTKKVVGIA 146

  Fly   173 IVSSATLHLFVPFAMTLMHGHV-VICVRVLQGLFEGVTYPACHGIWRFWAPPMERSRLATLAFSG 236
            ::.|:.|.|.:|.|..|  |.| .:..|.:|||.:|..|.....:|:.||||.|||||.|:|.||
Mouse   147 LLGSSLLTLCIPLAANL--GLVFFLATRAVQGLMQGTGYGGQFALWQKWAPPNERSRLCTIALSG 209

  Fly   237 SYAGVVVGLPLSGLLADAVGYQAPFYAYGVFGIIWYMFWIWLCFENPRKHPAISIPELKYIEKSL 301
            ...|:...|.:.|::::|:|:...||::|..|::..:.|..|.:::|..||.||.||.:||..||
Mouse   210 MTLGIFTVLLVGGIISEALGWPFVFYSFGGGGVLCSLLWFILIYDDPVSHPWISGPEREYILSSL 274

  Fly   302 GESAHPTMPSLKTTPWREMMRSMPVYAIIVANFCRSWNFYLLVLFQSSFLKHKFGFKVEEAGFVG 366
            .:........|   |.:.|::|:|::::.:......|.....:::..:::...|...:.:.||:.
Mouse   275 NQQFSSEEQPL---PIKAMLKSLPLWSMCLCTMTHQWLVNTFIMYTPTYISSVFKVNIRDNGFLS 336

  Fly   367 SLPHLIMTTIVPFGGMLADH-LRKNGILSTTNVRKLFNCGGFGMEGLFFL---FVAHSSTATGAM 427
            |||.::...:...||.|||. |.||..|.|  |||.....|.........   ::..|...|...
Mouse   337 SLPFIVAWVLGILGGWLADFLLSKNFRLIT--VRKFITLLGNAPPAALVAALPYIQSSYITTIIF 399

  Fly   428 FALTCGVAFSGFAISGYNVNHLDIAPRYASILMGLSNGIGTLAGIIVPYALDGLIQANPTGCWTT 492
            ..::||:.  ..:.:|..:|.|||||||||.|||.|.|:...:.::||......:..:....|..
Mouse   400 LTISCGLC--PLSQAGIYINALDIAPRYASFLMGTSRGLAHSSAVLVPIVAGFFLSQDSEFGWRN 462

  Fly   493 VFTLAACVHLVGCTFYGIFASGELQPWAEPPAEEQKV 529
            .|.:...|:|:|...|.:|...::|.|    |.|:|:
Mouse   463 FFFVVFAVNLLGLIIYLVFGKADVQEW----ARERKL 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGlut	NP_001245848.1	MFS	98..512	CDD:119392	126/449 (28%)
		MFS_1	101..475	CDD:284993	115/401 (29%)
Slc17a3	NP_598830.2	MFS_SLC17	42..482	CDD:340876	125/448 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838816
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.850