DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Eogt and eogt

DIOPT Version :9

Sequence 1:	NP_001259934.1	Gene:	Eogt / 33424	FlyBaseID:	FBgn0264672	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	XP_005155877.2	Gene:	eogt / 798087	ZFINID:	ZDB-GENE-120813-8	Length:	519	Species:	Danio rerio

Alignment Length:	508	Identity:	238/508 - (46%)
Similarity:	327/508 - (64%)	Gaps:	24/508 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 LDGFSLPSLPSEHLIRYL-NTFP--KLKQQLP-TNLTGKGTISSACWGHERDCTPAGRFQTPQCP 82
            ||..|| :||..|:..:| |..|  ||.::.| ........:..||||:|:.|:...||..|.|.
Zfish    27 LDYNSL-ALPQRHIPFFLHNNKPLAKLCKEDPLCPFKDALLLRKACWGYEKSCSAEHRFSYPVCT 90

  Fly    83 GEHTGWARSKEAQVRTFYNQADFGYIQEQLSQLTPQCVPTYLGDSSLECTHYLRFCRGRNLLFDF 147
            ...:|||.|.:|....|:.||||||::|:|:::...|.|:...||||:|:.::||||..||..|.
Zfish    91 SLDSGWANSIQAAQELFWKQADFGYVRERLNEMKTLCKPSKPADSSLKCSSHMRFCRATNLYLDL 155

  Fly   148 RGLEQREERIRYHMDVLGPGQLLGHCKLNRTRLSGEMEHIGSALQSWGPELRNFDVLPHPVLESG 212
            |...:..|  ||..|.|..|::.|||.|....|..|..| .|.||||..||:.:..|....|:.|
Zfish   156 RSPRRGHE--RYKEDFLEQGEIGGHCSLYSKALEAEGTH-KSPLQSWFAELQTYSELDFHPLDDG 217

  Fly   213 LCDVVVNTPTFIMKIDATYNMYHHFCDFFNLYASLFVNQSHPAAFNTDVQILIWET--YPYDSPF 275
            .|||:::.||..||:||..|||||||||.|||.|..:|.|    |:.|:.|::|:|  |.|...|
Zfish   218 HCDVIIDRPTVFMKLDAGVNMYHHFCDFVNLYISQHLNNS----FSRDINIVMWDTSVYGYGDLF 278

  Fly   276 RDTFKAFSQRPVWTLSDVEGKRVCFKNVVLPLLPRMIFGLFYNTPIIQGCSNSGLFRAFSEFILH 340
            .:|::|||...:..|.:::.|||||::....|||||.:|||||||:|..|.:.|||||||:.:||
Zfish   279 SETWQAFSDYDIIHLKNLDSKRVCFRDAFFSLLPRMRYGLFYNTPLISDCHSEGLFRAFSQHVLH 343

  Fly   341 RLQIPYKPPQQ-KIRITYLSRRTKYRQVLNEDELLAPLEANDKYDVQRV--SYERLPFTNQLAIT 402
            ||.:|...|:| ::|:|.|:|.|:||:::|:.||:..|:....::|:.|  .|:.:||..|:.:|
Zfish   344 RLSVPQDGPKQGQVRVTLLARSTEYRRIINQQELINALKTVPLFEVKLVDYKYKEMPFLEQIHVT 408

  Fly   403 RNTDILIGMHGAGLTHLLFLPNWACIFELYNCEDPNCYKDLARLRGVRYRTWEQRDLVYPQDEGH 467
            .|:||.|||||||||||||||:||.|||||||:|.:||:||||||||:|.||::||.|:|||:||
Zfish   409 HNSDIFIGMHGAGLTHLLFLPDWAVIFELYNCQDESCYRDLARLRGVQYMTWQKRDKVFPQDKGH 473

  Fly   468 HPEGGAHAKFTNYSFDVKEFVHLVDGAAEEILSHKEFPRRASENPSKTQRNEL 520
            ||..|.|.|||||:|||:||:.||..|||.:..|.::  ||     |..|.||
Zfish   474 HPTLGEHPKFTNYTFDVEEFMRLVLLAAEHVTRHPDW--RA-----KQSREEL 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eogt	NP_001259934.1	DUF563	232..454	CDD:282442	118/226 (52%)
eogt	XP_005155877.2	DUF563	237..460	CDD:309636	118/226 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595949
Domainoid	1	1.000	257	1.000	Domainoid score	I1983
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H65276
Inparanoid	1	1.050	458	1.000	Inparanoid score	I1551
OMA	1	1.010	-	-		QHG48941
OrthoDB	1	1.010	-	-		D339032at33208
OrthoFinder	1	1.000	-	-		FOG0005569
OrthoInspector	1	1.000	-	-		otm24834
orthoMCL	1	0.900	-	-		OOG6_105989
Panther	1	1.100	-	-	LDO	PTHR20961
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1388
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	13.000