DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eogt and pomgnt2

DIOPT Version :9

Sequence 1:	NP_001259934.1	Gene:	Eogt / 33424	FlyBaseID:	FBgn0264672	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001012384.2	Gene:	pomgnt2 / 497644	ZFINID:	ZDB-GENE-050522-242	Length:	585	Species:	Danio rerio

Alignment Length:	498	Identity:	127/498 - (25%)
Similarity:	198/498 - (39%)	Gaps:	89/498 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 KQQLPTNLTG--KGTISSACWGHERDCTPAGRFQTPQCPGEHTGWARSKE-AQVRTFYNQADFGY 107
            :..||..|.|  ...:::..|.:.|...     .|.|...|.....:|:| :|||..|:.|...
Zfish     7 RMNLPAVLNGLLVSVVAALLWKYVRLVE-----HTSQLEEELQLTRQSQEFSQVRIDYHGALLA- 65

  Fly   108 IQEQLSQLTPQCVPTYLGDSSLECT---HYLRFCRGRNLLFDFR-GLEQREERIRYHMD--VLGP 166
            :||..:::.              ||   |..|.||     ||:. ...:.||.:.:|.:  |:.|
Zfish    66 LQEHGTRMV--------------CTGKMHTDRICR-----FDYLCYCTEAEEFVFFHSNASVMLP 111

  Fly   167 GQLLGHCKLNRTRLSGEMEHIGSALQSWGPELRNFDVLPHPVLESGLCDVVVNTPTFIMKIDATY 231
            .  ||..:.....|.      .|:::....:..||..||...|:.....|.|...|.|:......
Zfish   112 N--LGSRRFQPALLD------LSSVEDHNTQYFNFLELPAAALKFMPKPVFVPDVTLILNRFNPD 168

  Fly   232 NMYHHFCDFFNLYASLFVNQSHPAAFNTDVQILIWETYPYDSPFRDTFKAF-SQRPVWTLSD--- 292
            |:.|.|.|  :|....:..|.: :..:.:.:::..|.:...:.| |.::.. |::|:  |.|
Zfish   169 NLMHIFHD--DLLPVYYTMQQY-SDLDDEARLVFMEGWGEGAHF-DLYRLLSSKQPL--LKDQLK 227

  Fly   293 VEGKRVCFKNVVLPLLPRMIFGLFYNTPIIQGCSNSGL-----FRAFSEFILHRLQIPYKPPQQK 352
            ..||.:||....:. |.:|.....|.....||...:.|     .|.|:.|::.||.|..:..::.
Zfish   228 TFGKLMCFTKSYVG-LSKMTTWYQYGFVQPQGPKANILISGNEIRQFASFLMERLNITREEEEED 291

  Fly   353 IRITYLSRRTKYRQVLNEDELLAPLEANDKYDVQRVSYERLPFTNQLAITRNTDILIGMHGAGLT 417
            .....:.:||..|.:|||.|||..|....:.....||.|...|.|.:.|.....:|:.||||.:.
Zfish   292 DDYIVVFKRTTNRLILNEAELLLALAQEFQMRTVTVSLEEQSFDNIIQIISRAAMLVSMHGAQMI 356

  Fly   418 HLLFLPNWACIFELY----NCEDPNCYKDLARLRG--VRYRTW----EQRDLVYPQDEGHHP--E 470
            ..:|||..|.:.||:    |.|....||.||.|.|  ::|..|    |:..:.:|.    .|  :
Zfish   357 TSMFLPRGAAVVELFPYGVNPEQYTPYKTLASLPGMDLQYVAWRNTMEENTVTFPD----RPWDQ 417

  Fly   471 GGAHAKFTNYSFDVKEFVHLVDGAAEEILSHKEFPRR-ASENP 512
            ||              .|||.....|.||:.||.||. ...||
Zfish   418 GG--------------IVHLEKEEQERILASKEVPRHLCCRNP 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eogt	NP_001259934.1	DUF563	232..454	CDD:282442	65/236 (28%)
pomgnt2	NP_001012384.2	DUF563	<326..402	CDD:301702	27/75 (36%)
pomgnt2	NP_001012384.2	FN3	498..585	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910