DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eogt and Pomgnt2

DIOPT Version :9

Sequence 1:	NP_001259934.1	Gene:	Eogt / 33424	FlyBaseID:	FBgn0264672	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001009437.1	Gene:	Pomgnt2 / 316091	RGDID:	1304827	Length:	580	Species:	Rattus norvegicus

Alignment Length:	413	Identity:	101/413 - (24%)
Similarity:	160/413 - (38%)	Gaps:	60/413 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 GDSSLEC---THYLRFCRGRNLLFDFRGLEQREERIRYH--MDVLGPGQLLGHCKLNRTRLSGEM 184
            |.:.:.|   ||..|.||.:.|.:.    .:.||.|.:|  ..|:.|.  ||..:.....|.
  Rat    63 GGTHMVCTGRTHTDRICRFKWLCYS----NEAEEFIFFHGNSSVMLPN--LGSRRFQPALLD--- 118

  Fly   185 EHIGSALQSWGPELRNFDVLPHPVLESGLCDVVVNTPTFIMKIDATYNMY------HHFCDFFNL 243
               .|.::....:..||..||...|.      .:..|.|:..:....|.:      |.|.|  :|
  Rat   119 ---LSTVEDHNAQYFNFVELPAAALR------FMPKPVFVPDVALIANRFNPDNLMHVFHD--DL 172

  Fly   244 YASLFVNQSHPAAFNTDVQILIWETYPYDSPFRDTFKAFSQRPVWTLSDVE--GKRVCFKNVVLP 306
            ....:..:..| ....:.::...|.:...:.| |.:|..|.:.....|.::  |:.:||.:..:.
  Rat   173 LPLFYTLRQFP-GLAQEARLFFMEGWGEGAHF-DLYKLLSPKQPLLRSQLKTLGRLLCFSHAFVG 235

  Fly   307 LLPRMIFGLFYNTPIIQGCSNSGL-----FRAFSEFILHRLQIPYKPPQQKIRITYLSRRTKYRQ 366
             |.::.....|.....||...:.|     .|.|:.|:..||.:.:...........:..||:.|.
  Rat   236 -LSKVTTWYQYGFVQPQGPKANILVSGNEIRQFTRFMTERLNVSHAGAPLGEEYILVFSRTQNRL 299

  Fly   367 VLNEDELLAPLEANDKYDVQRVSYERLPFTNQLAITRNTDILIGMHGAGLTHLLFLPNWACIFEL 431
            :|||.|||..|....:.....||.|...|.:.:.:..|..:|:.||||.|...||||..|.:.||
  Rat   300 ILNEAELLLELAQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTALFLPRGATVVEL 364

  Fly   432 Y----NCEDPNCYKDLARLRG--VRYRTWEQRDLVYPQDEGHHPEGGAHAKFTNYSFDVKEFVHL 490
            :    |.:....||.||.|.|  ::|..|  |::: .::...|||         ..:|.....||
  Rat   365 FPYAVNPDHYTPYKTLATLPGMDLQYVAW--RNMI-RENTVTHPE---------RPWDQGGITHL 417

  Fly   491 VDGAAEEILSHKEFPRR-ASENP 512
            .......||..:|.||. ...||
  Rat   418 DRAEQARILQSREVPRHLCCRNP 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eogt	NP_001259934.1	DUF563	232..454	CDD:282442	61/240 (25%)
Pomgnt2	NP_001009437.1	DUF563	<320..395	CDD:417760	27/76 (36%)
Pomgnt2	NP_001009437.1	FN3	493..580	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4698
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810