Protein Alignment Eogt and H12D21.10

DIOPT Version :9

• Sequence 1: NP_001259934.1
• Gene: Eogt / 33424
• FlyBaseID: FBgn0264672
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_506677.3
• Gene: H12D21.10 / 179990
• WormBaseID: WBGene00010386
• Length: 523
• Species: Caenorhabditis elegans
• Alignment Length: 514
• Identity: 205/514 - (39%)
• Similarity: 294/514 - (57%)
• Gaps: 36/514 - (7%)

  Fly    29 SLPSEHLIRYLNTFPKLKQ------QLPTNLTGKGTISSACWGHERDCTPAGRFQTPQCPGEHTG 87
            :||.:.|..::::.||.:|      :...||.     ::.|:|.|.||......:|   ..:.|.
 Worm    24 NLPRQLLEYHISSNPKFRQKCIEDEKCSINLN-----TTRCFGFEPDCDKINSLRT---RSKFTS 80

  Fly    88 WARSKEAQVR-TFYNQADFGYIQEQLSQLTPQCVPTYLGDSSLECTHYLRFCRGRNLLFDFRGLE 151
            ..::...:|. .|:.|.||||::.:|.: ...|...::..|:|.|:..|..|.|.|:.|||..|.
 Worm    81 CEQNLNPKVADLFFKQGDFGYLESRLVK-HDICTSDHVSLSTLSCSDDLTHCVGTNIFFDFSNLN 144

  Fly   152 QREERIRYHMDVLGPGQLLGHCKLNRTRLSGEMEHIGSALQSWGPELRNFDVLPHPVLESGLCDV 216
            .:.. .||..||:..|::.|.|.....::..:..::...|.||..||:||....:..::...||:
 Worm   145 IKTS-TRYRQDVIQAGRVGGKCSNFDEKVLKQNSNVKGYLMSWADELQNFRSSSNFQMDHDHCDI 208

  Fly   217 VVNTPTFIMKIDATYNMYHHFCDFFNLYASLFVNQSHPAAFNTDVQILIWETYP---YDSPFRDT 278
            :...||.|||:||..|:||||||||||||||.:||:    |:.||.|::|:|:|   .|..:..|
 Worm   209 IFEKPTIIMKLDAAVNLYHHFCDFFNLYASLHLNQT----FDQDVDIILWDTHPGGYNDHYYGVT 269

  Fly   279 FKAFSQRPVWTLSDVEGKRVCFKNVVLPLLPRMIFGLFYNTPIIQGCSNSGLFRAFSEFILHRLQ 343
            :||||:...:.|.:.:.|:||||.|::|||.|...|||||:|:::|||.|.:||.||:||||||.
 Worm   270 WKAFSKNQPFELKEFDQKKVCFKRVMMPLLARQRTGLFYNSPVVEGCSGSKMFRTFSQFILHRLG 334

  Fly   344 IPY-KPPQQKIRITYLSRRTKYRQVLNEDELLAPLEANDKYDVQRVSY-ERLPFTNQLAITRNTD 406
            |.. |...:|.||..|||.|.:|::||..|:|..|........:.|.| ||:||..||.||..||
 Worm   335 IRQPKADLEKARIVILSRSTAFRKILNIKEILRSLGHLPNVSTRVVDYNERIPFEKQLNITSKTD 399

  Fly   407 ILIGMHGAGLTHLLFLPNWACIFELYNCEDPNCYKDLARLRGVRYRTWEQR--DLVYPQDEGHHP 469
            |.|||||||||||||||:||.:||:|||.||.||.||||||||:|.||.:.  :|:...:||.||
 Worm   400 IFIGMHGAGLTHLLFLPDWAAVFEIYNCGDPGCYSDLARLRGVKYYTWPEAKINLIRSDEEGKHP 464

  Fly   470 EGG-AHAKFTNYSFDVKEFVHLVDGAAEEILSHKEF-------PRRASENPSKTQRNEL 520
            :.| .|.||.||..|..||...|....:.:.:|.:|       .|:..|..::..:.||
 Worm   465 QSGEKHLKFANYHVDPIEFREQVRKMVDHVRAHPKFINSRRAQKRKQEERMAEQNKKEL 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eogt	NP_001259934.1	DUF563	232..454	CDD:282442	124/226 (55%)
H12D21.10	NP_506677.3	DUF563	224..447	CDD:282442	124/226 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167270
Domainoid	1	1.000	249	1.000	Domainoid score	I1166
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H65276
Inparanoid	1	1.050	360	1.000	Inparanoid score	I1286
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48941
OrthoDB	1	1.010	-	-		D339032at33208
OrthoFinder	1	1.000	-	-		FOG0005569
OrthoInspector	1	1.000	-	-		oto18993
orthoMCL	1	0.900	-	-		OOG6_105989
Panther	1	1.100	-	-	LDO	PTHR20961
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3027
SonicParanoid	1	1.000	-	-		X1388
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.940