Protein Alignment Atxn7 and atxn7l2a

DIOPT Version :9

• Sequence 1: NP_001259932.1
• Gene: Atxn7 / 33423
• FlyBaseID: FBgn0031420
• Length: 971
• Species: Drosophila melanogaster
• Sequence 2: XP_005172962.1
• Gene: atxn7l2a / 692316
• ZFINID: ZDB-GENE-060519-13
• Length: 723
• Species: Danio rerio
• Alignment Length: 969
• Identity: 173/969 - (17%)
• Similarity: 279/969 - (28%)
• Gaps: 347/969 - (35%)

  Fly    51 GQKWQQVFDMEKVIKQLRTAEKTYLRGGKNSSAGADQQAKVQVQRLQSADMAYYDLAPKLASRDI 115
            ||.|....:...:.....:....|.:.||.:         ::...|:..||:.:...|......:
Zfish    27 GQSWSVWTERANLTASEGSDGDEYSKNGKKT---------METMTLRKEDMSIFGHYPGQDDFYL 82

  Fly   116 VLCSSCSGCYTKAGFQHHIALQHPSVWEATSSKVNPNPNGTAISSDSRLTATEISQEGGAIVPSS 180
            |:||.||.......|:.|...:|             .|.| .:.:..|.|.....|:......:.
Zfish    83 VVCSHCSQVVKPQAFEKHCERRH-------------GPLG-KLYAHLRSTPPPSQQQRPRHGHTP 133

  Fly   181 PTDTLSASTLSSCSNGSSSSASLQHPAAAGSSSTTSSSSSSRHKSSSSKSSSSSSSKGSSSTSAG 245
            |:...:||......|.....||.|.||         :....||..........|.|..|:|.
Zfish   134 PSHGATASWSGRNQNVGPPRASPQSPA---------TPPQFRHSKPPKDGVWHSPSNSSNSA--- 186

  Fly   246 SRSRSKSSKNRHHSSPAPALLESNHKESKGSKKSSAIAAPPVVAAVVKEEPPSVGAAPAAITMFS 310
                                    |.||                ||.|:.||        |....
Zfish   187 ------------------------HSES----------------AVFKQPPP--------IEPTR 203

  Fly   311 SSSNSSCSLPPTPTLGAASSEVAMGVNYSPAQLQTDAEKLPELQ---------PKKKLKGSSDHR 366
            ||...:...||.|..|.           ||.:|...||: |:.|         |...|:|:..|:
Zfish   204 SSPPPAHRDPPWPHGGP-----------SPNRLPPAAER-PQSQRGEAASAPVPSGHLRGTKTHK 256

  Fly   367 IKAEKEKNKDKSLVNSYEQQQVLSELDQAVSSITGAVSAEQVAPDEEELPLPNTSDENSISQTLD 431
            :.::||.:.||..
Zfish   257 MVSKKECDLDKHC---------------------------------------------------- 269

  Fly   432 EMLDSKLINEILNNFDESALDTSQQQSQQQAQNGSLSHPAQATKRLRFEDGTIGEDYAVYQQQAV 496
                             ..|||.:::...:....::                    ::::|::.|
Zfish   270 -----------------GVLDTERKKVCTRLLTCNI--------------------HSIHQRRKV 297

  Fly   497 QQVYGEEEHQQELTTIDAMQLQQLIYQQQQMLEQQQLQEQQQQQQQDQKLQDHEQQRQFSVYNVP 561
            |   |..::..:|..                               :.|:....::|   |...|
Zfish   298 Q---GRSKNFDQLVA-------------------------------ELKMSSKARER---VSQAP 325

  Fly   562 SLTDEAMVNPQQQQLEEHMILPSIIYEITESNPVSMLEQKVLAEFLTNAGYENVDVNVVQSGGIQ 626
            ..:....|:|:..:  :....||....:|.|           ..|.|....|:::.:       :
Zfish   326 ESSSAPSVSPEPPR--DTPAPPSCRRPLTNS-----------PAFRTPVSSESIEED-------K 370

  Fly   627 TNL-SSGTEANQLADELADFEFSKLETVSDTVKTVKLEAKAASQPPTTNPQINHHPSLANAKYHE 690
            |:| .|.|.|:   ..|.....|..|:..:|                     |..|    |.:|.
Zfish   371 THLEESSTRAH---SPLTQAHISGDESEGET---------------------NEEP----ADWHS 407

  Fly   691 DSYFNVMLYSGAPRPLAMNTFGMVKLPQGLGVTFRKNLLTTRKANNNLLSLSGGNHLGVVGQLAR 755
            ..:.        |:|.|:.:||...|..|: .||.:.|...|.|.:.::......||......|.
Zfish   408 TPWH--------PKPAALCSFGSHSLGHGV-FTFDRRLHHLRSAMSAMVESHLSAHLWKKIPQAS 463

  Fly   756 TPPPPSPALSNGLPGKNPASGRTIYAQRSNVIA--QDRLRCNKRALVGGKAGG------GSSGSP 812
            .|...||   ...|...|||..:| :|.|...|  .:.....|.:.......|      .||.|.
Zfish   464 DPQSQSP---QAKPAAVPASPSSI-SQHSKPRAGSHNTTSSLKTSFYSSHGPGKEPNPQSSSTSK 524

  Fly   813 GVMTAKRLNELLMGKAKKEEKPPPDSEDGGEQPTKDKERDKEED----------NKLTFSFYEKR 867
            ....::......:|::..:..|.......| :|:|.:.|.:|.|          .|...||.:..
Zfish   525 AYAQSENSGSSKLGRSPSQSGPGRPKNPVG-RPSKQQMRLRESDRTPTPDAAALRKRKASFEDSD 588

  Fly   868 RRLLAGKLEQLQPLGRP--SFTLP----------LQSNHNASQSQSHSPQQLLKKQLLRTLSDS- 919
            ..:...|....|...||  |.|.|          |.....|..|.||||.....|:..::..||
Zfish   589 SAVSPDKNCVPQNKSRPLISKTPPSASHGQTNGSLSPGSKARPSDSHSPSSWAFKRTHQSAPDSR 653

  Fly   920 --SSNMNISNMNNISNLNSSNTPSANSNPP----------------W---KGNSSNPGG 957
              .|.:.:|:.::.|  ......|:.|:||                |   ||:..:.||
Zfish   654 GLDSGLRVSSFDHKS--LGKKRKSSGSSPPSKPHRLPTSPHSGFYTWKESKGSGLSVGG 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atxn7	NP_001259932.1	None
atxn7l2a	XP_005172962.1	SCA7	250..312	CDD:285508	14/184 (8%)
		DHQ_Fe-ADH	322..>385	CDD:295526	15/85 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4140
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900