DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atxn7 and atxn7l2b

DIOPT Version :9

Sequence 1:	NP_001259932.1	Gene:	Atxn7 / 33423	FlyBaseID:	FBgn0031420	Length:	971	Species:	Drosophila melanogaster
Sequence 2:	NP_001002655.2	Gene:	atxn7l2b / 436928	ZFINID:	ZDB-GENE-040718-403	Length:	666	Species:	Danio rerio

Alignment Length:	228	Identity:	54/228 - (23%)
Similarity:	85/228 - (37%)	Gaps:	41/228 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   193 CSN----------GSSSSASLQHPAAAGSSSTTSSSSSSRHKSSSSKSSSSSSSKGSSSTSAGSR 247
            |||          .:.|||.: |..:...:||:..|..|..|:||.:.:.:.|:.|.......|:
Zfish   430 CSNQQQITYNSHDATRSSAPI-HITSTLRTSTSGQSEPSNLKASSKRPTKAQSASGPVRPRQTSK 493

  Fly   248 SRSKSSKNRH-HSSPAPALLESNHKESKGSKKSSAIAAPPVVAAVVKEEPPSVGAAPAAITMFSS 311
            ..|..:..|. ..||..:....:.||.|.|...|.:...|    ..::...|:.:.|..  :|:.
Zfish   494 QASLQTGFRELQDSPTASKRRKSPKEDKDSSGQSKMLFVP----HQRDHQSSLISPPHG--LFNG 552

  Fly   312 SSNSSCSLPPTPTLGAASSEVAMGVNYSPAQLQTDAEKLPELQPKKKLKGSS--DHR-----IKA 369
            :..||....|..|.|.        |..|||.:...:.     .|:.:..|||  .||     :|.
Zfish   553 THPSSSKTRPPETKGR--------VKQSPALISISSP-----SPECERGGSSGLSHRSDGFELKG 604

  Fly   370 EKEKNKDKS---LVNSYEQQQVLSELDQAVSSI 399
            .|.|....|   ..:...:..:||.|.|..|.:
Zfish   605 RKRKTSGASPPKNTSCAPKANILSPLSQTHSGL 637

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
Atxn7	NP_001259932.1	None
atxn7l2b	NP_001002655.2	SCA7	221..277	CDD:285508
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4140
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900