DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3609 and SPAC513.06c

DIOPT Version :9

Sequence 1:	NP_001188684.1	Gene:	CG3609 / 33421	FlyBaseID:	FBgn0031418	Length:	335	Species:	Drosophila melanogaster
Sequence 2:	NP_593980.1	Gene:	SPAC513.06c / 2543473	PomBaseID:	SPAC513.06c	Length:	368	Species:	Schizosaccharomyces pombe

Alignment Length:	366	Identity:	113/366 - (30%)
Similarity:	170/366 - (46%)	Gaps:	55/366 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SKLIRWGIASAGKISEDFVIALSTLPSSDHKVQ----AVAARALD-RAQEFATKHGI---PKALG 58
            |.:|.||...||.|:..|...|..:|.. ||||    |||.|..: ||..||..|..   |||.|
pombe     8 SPVIHWGFLGAGSIAAVFAKDLVGVPER-HKVQHEIVAVATRDSEHRASSFAKNHCAPCKPKAYG 71

  Fly    59 SYEELAKSTDVDVVYIGTLNPQHYEVALLMLNNGKHVLCEKPLAMNKKQVEGILAAAKANKRFFM 123
            |||||.|...||:|||.:.:||||||..|.|.|.|.|||||||.:|..:...::..|:|...||.
pombe    72 SYEELVKDDKVDIVYISSTHPQHYEVVKLALLNDKAVLCEKPLTINYPEALELVELARARNLFFA 136

  Fly   124 EAVWSRFFPSYQRVKELISSGQL-GQ----VKDVEVNFGF-PMPHVDRLQKRELGGGVVYDLGIY 182
            |..|.||:|..:..|.|:...:: |.    ..|...:|.| .:|...||:...||.||:.|:|:|
pombe   137 EGFWIRFYPIVKAAKTLLHEDRVCGDHFRLFVDFSQDFRFRELPSESRLRTVSLGAGVLLDMGVY 201

  Fly   183 TIQVSQWAFQEKPEKIESKGTLNAEGI----------DDDVSATLTYSGGRTARMRFSSKE---- 233
            .:..|:....:.|:..:.:.|:::..:          |...:.||.:....:..|..:|.:
pombe   202 PLTWSRLLLYDDPKNEKQEPTVSSNALTFEDHNGDIGDYTTAVTLVFPKTESIAMLCTSMDRGKM 266

  Fly   234 -----KL----GNTAVIKGTKGQVTLIDFWSPN--KLIDIDGQEKEWLPPKGKYATNYANSEAMR 287
                 ||    ||...|.|        |.:.|.  |||...|:.:       .:..::.::....
pombe   267 SDDFLKLDGENGNQLFISG--------DCYRPQSIKLIRASGETE-------VFDFSFDDATGFF 316

  Fly   288 YEAEAVRQSIIAGEVENKNVTYADSLIFAEIEDTIRKQIGV 328
            ||.:||.:.::....|...:.:.::|...::.|.||:||.|
pombe   317 YEQDAVAECLLKNMKEAPEIPHEETLKMMQLTDQIRRQINV 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3609	NP_001188684.1	MviM	5..292	CDD:223745	102/325 (31%)
		GFO_IDH_MocA	5..123	CDD:279716	58/125 (46%)
		GFO_IDH_MocA_C	138..>198	CDD:304482	18/65 (28%)
SPAC513.06c	NP_593980.1	MviM	8..355	CDD:223745	110/362 (30%)
SPAC513.06c	NP_593980.1	GFO_IDH_MocA	11..139	CDD:279716	60/128 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	1.000	Domainoid score	I2037
eggNOG	1	0.900	-	-		E1_COG0673
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8709
Inparanoid	1	1.050	141	1.000	Inparanoid score	I1364
OMA	1	1.010	-	-		QHG57478
OrthoFinder	1	1.000	-	-		FOG0001373
OrthoInspector	1	1.000	-	-		otm47012
orthoMCL	1	0.900	-	-		OOG6_101004
Panther	1	1.100	-	-	LDO	PTHR22604
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1924
SonicParanoid	1	1.000	-	-		X868
TreeFam	1	0.960	-	-
	14	13.860