Protein Alignment CG3597 and DHDH

DIOPT Version :9

• Sequence 1: NP_001259930.1
• Gene: CG3597 / 33420
• FlyBaseID: FBgn0031417
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_055290.1
• Gene: DHDH / 27294
• HGNCID: 17887
• Length: 334
• Species: Homo sapiens
• Alignment Length: 334
• Identity: 129/334 - (38%)
• Similarity: 190/334 - (56%)
• Gaps: 12/334 - (3%)

  Fly     7 LNWGIAAAGRITQDFVTALGTVEKSRHVVVAVADVDGQRAQQFAQRNQIPRHYDGFDALALDREV 71
            |.|||.:.|.|:.||...|.|:.:|.|.|||||..|..||::|||::.||:.|..::.||.|..|
Human     3 LRWGIVSVGLISSDFTAVLQTLPRSEHQVVAVAARDLSRAKEFAQKHDIPKAYGSYEELAKDPSV 67

  Fly    72 EVVYVGTLNPFHYAVVHLMLARGKNVLCETPMCLSVEQAKELYTLAEQRGVFLMEGNSMWSRFFP 136
            ||.|:||.:|.|.|.|.|.||.||.||||.|..::..:.:|:...|..|.:||||  ::|:||||
Human    68 EVAYIGTQHPQHKAAVMLCLAAGKAVLCEKPTGVNAAEVREMVAEARSRALFLME--AIWTRFFP 130

  Fly   137 SYDRLRELLKNDVIGEVTQVKVQHGFRLAHMERVCNRSLGGSILMDIGIYALQLGQFVF-GVSPV 200
            :.:.||.:|....:|::...:.:.|..|.|:.|..:|:..|..|:|||||.:|....|| |..|.
Human   131 ASEALRSVLAQGTLGDLRVARAEFGKNLIHVPRAVDRAQAGGALLDIGIYCVQFTSMVFGGQKPE 195

  Fly   201 KILPSGTQLNKERVDVQIDFMLDY-GD--GRRLVALVTGLENLENDAVITGTKGEIKLSN-YWCC 261
            ||...|.: ::..||..:..:|.| |:  |....::..   .|.|.|.::||||.::|.| .||.
Human   196 KISVVGRR-HETGVDDTVTVLLQYPGEVHGSFTCSITV---QLSNTASVSGTKGMVQLLNPCWCP 256

  Fly   262 TQISRSNAPPESWPLPRAKFDFHYTNTCGLRYEAEEVRRCIEKRLLESPKFTHAESLELAAIADE 326
            |::.......| :|||....|.::.|..|:.|||:.|..|:.|.:.|||....:||..||.|.:|
Human   257 TELVVKGEHKE-FPLPPVPKDCNFDNGAGMSYEAKHVWECLRKGMKESPVIPLSESELLADILEE 320

  Fly   327 IRRQIGVVY 335
            :|:.|||.:
Human   321 VRKAIGVTF 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3597	NP_001259930.1	MviM	7..332	CDD:223745	126/329 (38%)
		GFO_IDH_MocA	7..127	CDD:279716	55/119 (46%)
		GFO_IDH_MocA_C	142..228	CDD:304482	28/89 (31%)
DHDH	NP_055290.1	MviM	1..326	CDD:223745	126/329 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160343
Domainoid	1	1.000	115	1.000	Domainoid score	I6039
eggNOG	1	0.900	-	-		E1_COG0673
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57478
OrthoDB	1	1.010	-	-		D351032at33208
OrthoFinder	1	1.000	-	-		FOG0001373
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22604
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X868
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.820