DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3597 and SPAC513.06c

DIOPT Version :9

Sequence 1:	NP_001259930.1	Gene:	CG3597 / 33420	FlyBaseID:	FBgn0031417	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_593980.1	Gene:	SPAC513.06c / 2543473	PomBaseID:	SPAC513.06c	Length:	368	Species:	Schizosaccharomyces pombe

Alignment Length:	359	Identity:	116/359 - (32%)
Similarity:	169/359 - (47%)	Gaps:	40/359 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LNWGIAAAGRITQDFVTAL-GTVE--KSRHVVVAVADVDGQ-RAQQFAQRNQI---PRHYDGFDA 64
            ::||...||.|...|...| |..|  |.:|.:||||..|.: ||..||:.:..   |:.|..::.
pombe    11 IHWGFLGAGSIAAVFAKDLVGVPERHKVQHEIVAVATRDSEHRASSFAKNHCAPCKPKAYGSYEE 75

  Fly    65 LALDREVEVVYVGTLNPFHYAVVHLMLARGKNVLCETPMCLSVEQAKELYTLAEQRGVFLMEGNS 129
            |..|.:|::||:.:.:|.||.||.|.|...|.||||.|:.::..:|.||..||..|.:|..||
pombe    76 LVKDDKVDIVYISSTHPQHYEVVKLALLNDKAVLCEKPLTINYPEALELVELARARNLFFAEG-- 138

  Fly   130 MWSRFFPSYDRLRELLKND-VIGEVTQ--VKVQHGFRLAHM---ERVCNRSLGGSILMDIGIYAL 188
            .|.||:|.....:.||..| |.|:..:  |.....||...:   .|:...|||..:|:|:|:|.|
pombe   139 FWIRFYPIVKAAKTLLHEDRVCGDHFRLFVDFSQDFRFRELPSESRLRTVSLGAGVLLDMGVYPL 203

  Fly   189 QLGQFVFGVSP--VKILP--SGTQLNKERVDVQIDFMLDYGDGRRLVALVTGLENLENDAVITGT 249
            ...:.:....|  .|..|  |...|..|      |...|.||....|.||  ....|:.|::..:
pombe   204 TWSRLLLYDDPKNEKQEPTVSSNALTFE------DHNGDIGDYTTAVTLV--FPKTESIAMLCTS 260

  Fly   250 KGEIKLSNYWCCTQ--------ISRSNAPPESWPLPRAK-----FDFHYTNTCGLRYEAEEVRRC 301
            ....|:|:.:....        ||.....|:|..|.||.     |||.:.:..|..||.:.|..|
pombe   261 MDRGKMSDDFLKLDGENGNQLFISGDCYRPQSIKLIRASGETEVFDFSFDDATGFFYEQDAVAEC 325

  Fly   302 IEKRLLESPKFTHAESLELAAIADEIRRQIGVVY 335
            :.|.:.|:|:..|.|:|::..:.|:|||||.|.|
pombe   326 LLKNMKEAPEIPHEETLKMMQLTDQIRRQINVTY 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3597	NP_001259930.1	MviM	7..332	CDD:223745	113/354 (32%)
		GFO_IDH_MocA	7..127	CDD:279716	47/126 (37%)
		GFO_IDH_MocA_C	142..228	CDD:304482	27/95 (28%)
SPAC513.06c	NP_593980.1	MviM	8..355	CDD:223745	112/353 (32%)
SPAC513.06c	NP_593980.1	GFO_IDH_MocA	11..139	CDD:279716	49/129 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	1.000	Domainoid score	I2037
eggNOG	1	0.900	-	-		E1_COG0673
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	141	1.000	Inparanoid score	I1364
OMA	1	1.010	-	-		QHG57478
OrthoFinder	1	1.000	-	-		FOG0001373
OrthoInspector	1	1.000	-	-		otm47012
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22604
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1924
SonicParanoid	1	1.000	-	-		X868
TreeFam	1	0.960	-	-
	12	11.960