Protein Alignment Axud1 and CSRNP1

DIOPT Version :9

• Sequence 1: NP_001259928.1
• Gene: Axud1 / 33419
• FlyBaseID: FBgn0261647
• Length: 852
• Species: Drosophila melanogaster
• Sequence 2: NP_001307488.1
• Gene: CSRNP1 / 64651
• HGNCID: 14300
• Length: 609
• Species: Homo sapiens
• Alignment Length: 662
• Identity: 185/662 - (27%)
• Similarity: 254/662 - (38%)
• Gaps: 169/662 - (25%)

  Fly   223 KPKEDELRDGGSDSGLGSETSALLKDQAEKEAEPEIQKKVETKPIRSNLKRRLEDSESDAIDLVP 287
            |.|.|:|.:..|.....|.:|..    ..:...|.           |::.|..:..|....|.:|
Human    26 KRKFDQLDEDNSSVSSSSSSSGC----QSRSCSPS-----------SSVSRAWDSEEEGPWDQMP 75

  Fly   288 ----DMSAP----PVAPQKRTKRS----INFDEVKVFYFPRQQGFSCVPTAGGCTLGMGARHVGF 340
                |...|    |::..||.:|.    :.||.:.||||||.|||:.||:.|||||||..||...
Human    76 LPDRDFCGPRSFTPLSILKRARRERPGRVAFDGITVFYFPRCQGFTSVPSRGGCTLGMALRHSAC 140

  Fly   341 KTMTLAEHAAELRRA-HRSQNQELQ-----------------------PRGSSSDDSEESEEDYL 381
            :..:|||.|.|..|| |....|.|:                       |....:.|....|||..
Human   141 RRFSLAEFAQEQARARHEKLRQRLKEEKLEMLQWKLSAAGVPQAEAGLPPVVDAIDDASVEEDLA 205

  Fly   382 SEGSGSDAEDGSNGFLQPVTPKQRRALLKAAGVRKIDASEKSECRDIRNSREVCGCSCREFCDPE 446
            ...:|...|:.|  ||||...::|||||:|:|||:||..||.|.:.:|.|||.|||.|...||||
Human   206 VAVAGGRLEEVS--FLQPYPARRRRALLRASGVRRIDREEKRELQALRQSREDCGCHCDRICDPE 268

  Fly   447 TCACSQAGIKCQVDRAMFPCGCTREACGNTVGRVEFNPTRVRTHYIHTVMRLDLEQRQGSVQGVQ 511
            ||:||.||||||:|...|||||.||.|.|.:||||||..||:||:|||:.||.|||...|.:.::
Human   269 TCSCSLAGIKCQMDHTAFPCGCCREGCENPMGRVEFNQARVQTHFIHTLTRLQLEQEAESFRELE 333

  Fly   512 GGHLQPQQQQPSQQTIGYSPVGTAGSTSAYFLQTQSNYSSGYASPAYTPESSVSYYQQQVQQPGV 576
            .    |.|..|                               .||.              ::..|
Human   334 A----PAQGSP-------------------------------PSPG--------------EEALV 349

  Fly   577 PTAGQLIPQQQQAQSQSYAGYAQLDSLDSGLFASGSNATPSYGELYQSLSYGSTQITSYTAAYQQ 641
            ||.....|........:.......||..:...|||::..|.                     ...
Human   350 PTFPLAKPPMNNELGDNSCSSDMTDSSTASSSASGTSEAPD---------------------CPT 393

  Fly   642 HSASPAVAVAPGAPSSCAYSSCAVPSVPPYGNATTTASSNVPYQTTAVSMTAASTSASPSRLVGN 706
            |...|.....||....      ::..:..:.::..........:.:..::...| ...|:.:.|
Human   394 HPGLPGPGFQPGVDDD------SLARILSFSDSDFGGEEEEEEEGSVGNLDNLS-CFHPADIFG- 450

  Fly   707 PVGSATASPATVSSSPATASGNEFISLSTPIASSSRLSQINDLLQHNRNTTAALVAVSEGLSGGR 771
                 |:.|..::|...:.||..|.|               .:|..|.|..|:..     |:||.
Human   451 -----TSDPGGLASWTHSYSGCSFTS---------------GVLDENANLDASCF-----LNGGL 490

  Fly   772 TSSSASTIDSIDTPPIVDDGQQ-------RGCMSFE---ALPPPLVNPAPIVAVVENKLPPMALP 826
            ..|...::.....||.:|.|:.       ..|.|||   |||...:.|......|.:.|.  .:.
Human   491 EGSREGSLPGTSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPHYTSQKVSDSLD--NIE 553

  Fly   827 APHAP-PSAPQP 837
            |||.| |....|
Human   554 APHFPLPGLSPP 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Axud1	NP_001259928.1	CSRNP_N	301..500	CDD:292638	106/226 (47%)
		PHA03255	643..>786	CDD:165513	21/142 (15%)
CSRNP1	NP_001307488.1	CSRNP_N	101..322	CDD:292638	105/222 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160219
Domainoid	1	1.000	218	1.000	Domainoid score	I2657
eggNOG	1	0.900	-	-		E1_KOG3813
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001585
OrthoInspector	1	1.000	-	-		otm40615
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13580
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3357
SonicParanoid	1	1.000	-	-		X1316
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.830