DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Axud1 and Csrnp2

DIOPT Version :9

Sequence 1:	NP_001259928.1	Gene:	Axud1 / 33419	FlyBaseID:	FBgn0261647	Length:	852	Species:	Drosophila melanogaster
Sequence 2:	NP_700456.1	Gene:	Csrnp2 / 207785	MGIID:	2386852	Length:	534	Species:	Mus musculus

Alignment Length:	535	Identity:	171/535 - (31%)
Similarity:	233/535 - (43%)	Gaps:	154/535 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   269 SNLKRRLED--------------SESDAIDLVPDMSAP------PVAPQKRTK----RSINFDEV 309
            |.|||:.:|              |.||:.|....::.|      |.:..||.|    :::.||:|
Mouse     7 SGLKRKFDDVDVGSSVSNSDDEMSSSDSADSCDSLNPPTTASFTPTSILKRQKQLRRKNVRFDQV 71

  Fly   310 KVFYFPRQQGFSCVPTAGGCTLGMGARHVGFKTMTLAEHAAELRRAHR-------------SQNQ 361
            .|:||.|:|||:.||:.||.:|||..||...::.||.|.|.|....||             ::..
Mouse    72 TVYYFARRQGFTSVPSQGGSSLGMAQRHNSVRSYTLCEFAQEQEVNHREILREHLKEEKLHAKKM 136

  Fly   362 ELQPRGSSSDDSEESEEDYLSEGSGSDAE-DGSN------GFLQPVTPKQRRALLKAAGVRKIDA 419
            :|...|:    .|..|.|.|:....||.: |..|      .||||:..|:|||||:|:||.:|||
Mouse   137 KLTKNGT----VESVEADGLTLDDVSDEDIDVENVEVDDYFFLQPLPTKRRRALLRASGVHRIDA 197

  Fly   420 SEKSECRDIRNSREVCGCSCREFCDPETCACSQAGIKCQVDRAMFPCGCTREACGNTVGRVEFNP 484
            .||.|.|.||.|||.|||.||.:||||.||||||||||||||..|||||:|:.|||..||:||||
Mouse   198 EEKQELRAIRLSREECGCDCRLYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNP 262

  Fly   485 TRVRTHYIHTVMRLDLE-QRQGS--------VQGVQGG-----------------HLQPQQQ--- 520
            .||||||:||:|:|:|| :||.|        :.|.|..                 |||..::
Mouse   263 IRVRTHYLHTIMKLELESKRQVSRPAAEEEPLPGAQSSQTQDFQEFIAENETAVMHLQSAEELER 327

  Fly   521 --------------QPSQQTIGY----SPVGT-----AGSTSAYFLQTQSN-------YSSGYAS 555
                          ..|.:::|.    .|:..     .|..:...:|.|..       ::.....
Mouse   328 LKAEEDSSGSSASLDSSMESLGVCILEEPLAVPQELCPGLAAPILIQAQLPPGSSVLCFTENSEH 392

  Fly   556 PAYTPESSVSY-------YQQQVQQPGVPTAGQLIPQQQQAQSQSYAGYAQLDSLDSGLFASGSN 613
            ||.:|.||.||       |.|..|:|.|....:                            |||.
Mouse   393 PAASPMSSPSYLNSGPLVYYQVEQRPVVGVKAE----------------------------SGSE 429

  Fly   614 ATPSYGELYQSLSYGSTQITSYTAAYQQHSAS---PAVAVAPG----APSSCAYSSCAVPSVPPY 671
            ..|:.....:.||..|..:||..|.....||:   |.|.....    .|..|.........:.|
Mouse   430 EGPASFPKEKDLSVFSLPVTSLVACGPSASAALCKPEVGKTSSLNKLLPEDCGLKEPESEDLHP- 493

  Fly   672 GNATTTASSNVPYQT 686
                :.:.|::|::|
Mouse   494 ----SWSPSSLPFRT 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Axud1	NP_001259928.1	CSRNP_N	301..500	CDD:292638	110/222 (50%)
Axud1	NP_001259928.1	PHA03255	643..>786	CDD:165513	10/51 (20%)
Csrnp2	NP_700456.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..52		10/44 (23%)
		CSRNP_N	63..278	CDD:292638	109/218 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	479..534		5/31 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850593
Domainoid	1	1.000	218	1.000	Domainoid score	I2639
eggNOG	1	0.900	-	-		E1_KOG3813
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001585
OrthoInspector	1	1.000	-	-		otm42691
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13580
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3357
SonicParanoid	1	1.000	-	-		X1316
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.920