DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Axud1 and csrnp3

DIOPT Version :9

Sequence 1:	NP_001259928.1	Gene:	Axud1 / 33419	FlyBaseID:	FBgn0261647	Length:	852	Species:	Drosophila melanogaster
Sequence 2:	XP_004917760.2	Gene:	csrnp3 / 100490263	XenbaseID:	XB-GENE-954411	Length:	579	Species:	Xenopus tropicalis

Alignment Length:	602	Identity:	181/602 - (30%)
Similarity:	247/602 - (41%)	Gaps:	193/602 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   271 LKRRLEDSE--------------------SDAIDLVPDMSAPPVAPQ---KRTKR----SINFDE 308
            |||:.|:.|                    :|:.|.|...|:....|.   ||.||    ::.|:.
Frog     5 LKRKFEEVEGSSPCSSIQESDDDISSSESADSSDSVNPSSSNHFTPSSILKREKRLRAKNVRFNC 69

  Fly   309 VKVFYFPRQQGFSCVPTAGGCTLGMGARHVGFKTMTLAEHAAELRRAHR-------------SQN 360
            |.|:||.|:|||:.||:.||.||||.:||...:..||.|.|.|..|.|:             |..
Frog    70 VTVYYFTRRQGFTSVPSQGGSTLGMSSRHNSVRQYTLGEFALEQDRLHKEMLRDHLREEKLNSLK 134

  Fly   361 QELQPRGSSSDDSEESEEDYLSEGSGSD-----AEDGSNGFLQPVTPKQRRALLKAAGVRKIDAS 420
            |::...|:.  :|||:....|.:.|..|     .|.....||||:..|:|||||:|:||:|||..
Frog   135 QKITKNGTV--ESEEASILTLDDISDDDIDLDNTEVDEYFFLQPLPTKKRRALLRASGVKKIDVE 197

  Fly   421 EKSECRDIRNSREVCGCSCREFCDPETCACSQAGIKCQVDRAMFPCGCTREACGNTVGRVEFNPT 485
            ||.|.|.||.|||.|||.||.|||||||.||.|||||||||..|||||::|.|.||.||:||||.
Frog   198 EKHELRAIRLSREDCGCDCRIFCDPETCTCSLAGIKCQVDRMSFPCGCSKEGCSNTAGRIEFNPI 262

  Fly   486 RVRTHYIHTVMRLDLE--QRQGSVQG--------------VQGGH-----------LQPQQQQ-- 521
            |||||::||:|:|:||  :.|.:..|              .|.||           ::.:.|.
Frog   263 RVRTHFLHTIMKLELEKNREQQATLGNGCHSDVNSLASALAQNGHSVEYSIAENFEIESESQSAL 327

  Fly   522 ----------------------------PSQQTIGYSPVGT----------AGSTSAYFLQTQSN 548
                                        ....|...||..:          .|..|..|.:..|.
Frog   328 MHFQSSDHLDCNGDDEEEDDGSSYCSGVTDSSTQSLSPSESDDDDDEDDEDDGDKSDEFSEVISP 392

  Fly   549 ------------YSSG-------YASPAYTPESSVSYYQ---------QQVQQP-----GVPTAG 580
                        ||:|       ..:.:|...||..|||         .|:.:|     .|..|.
Frog   393 HDDNITGHSVLCYSNGNTMHDNHLKNASYYSNSSALYYQIENHNSGTTNQIPEPYPDRSSVKNAT 457

  Fly   581 -QLIPQQQQAQSQSYAGYAQLDSLDSGLFASGSNATPSYGELYQSLSYGSTQITSYTAAYQQHSA 644
             .|:|...:|  :.:|.|::                 .:.|.:.|..|.:|
Frog   458 LNLVPYNMRA--EQFADYSR-----------------QHEESFSSCHYPTT-------------- 489

  Fly   645 SPAVAVAPGAPSSCAYSSCAVPSVPPYGNATTTASSNVPYQTTAVSMTAASTSASPSRLVGNPVG 709
            :|:|.|...|..:...:||        .|......||:|    .|...:...|:||...|.|..|
Frog   490 NPSVIVCCAATENENNTSC--------HNLYPELRSNLP----QVEFHSYLKSSSPDGFVPNLNG 542

  Fly   710 SATASPATVSSSPATAS 726
            |:..||..::.:|...|
Frog   543 SSHHSPELLNDNPVNLS 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Axud1	NP_001259928.1	CSRNP_N	301..500	CDD:292638	110/220 (50%)
Axud1	NP_001259928.1	PHA03255	643..>786	CDD:165513	22/84 (26%)
csrnp3	XP_004917760.2	CSRNP_N	61..278	CDD:406427	108/218 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	215	1.000	Domainoid score	I2660
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001585
OrthoInspector	1	1.000	-	-		otm47793
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1316
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.000