DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab5 and rabl2b

DIOPT Version :9

Sequence 1:	NP_001259925.1	Gene:	Rab5 / 33418	FlyBaseID:	FBgn0014010	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_001072451.1	Gene:	rabl2b / 779905	XenbaseID:	XB-GENE-979695	Length:	225	Species:	Xenopus tropicalis

Alignment Length:	169	Identity:	59/169 - (34%)
Similarity:	92/169 - (54%)	Gaps:	9/169 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 KLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTICIEDTVVKFEIWDTAGQERYHSLA 95
            |::.||:||||||.|:.||:...|...|.||........:.|::...|..:.||||||||:||:.
Frog    23 KIICLGDSAVGKSKLMERFLMDGFRPQQLSTFALTLYKYSTCVDGNTVLVDFWDTAGQERFHSMH 87

  Fly    96 PMYYRGAQAAIVVYDIQNQDSFQRAKTWVKELHKQASPNIVIALAGNKADLSNIRVVEFDEAKQY 160
            ..||..|.|.|:|:|:|.:.:::....|.:|| ::..|.|...:..||.| ::|||.:  :...:
Frog    88 ASYYHKAHACIMVFDVQRKITYKNLGKWYQEL-REYRPEIPCIVVANKID-ADIRVTQ--KGFNF 148

  Fly   161 AEENGLLFMETSAKTGMNVNDIF-----LAIAKKLPKND 194
            .:::.|.|...||..|.||..:|     ||::.|....|
Frog   149 GKKHNLPFYFVSAADGTNVVKLFKDAIKLAVSYKQNSQD 187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab5	NP_001259925.1	Rab5_related	29..191	CDD:206653	58/164 (35%)
rabl2b	NP_001072451.1	RabL2	22..182	CDD:133324	57/162 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1340129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010