DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab5 and Rab38

DIOPT Version :9

Sequence 1:	NP_001259925.1	Gene:	Rab5 / 33418	FlyBaseID:	FBgn0014010	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_082514.4	Gene:	Rab38 / 72433	MGIID:	1919683	Length:	211	Species:	Mus musculus

Alignment Length:	181	Identity:	56/181 - (30%)
Similarity:	101/181 - (55%)	Gaps:	15/181 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 NKSCQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTICIE-DTVVKFEIWDTAGQ 88
            :|...:||:::|:..|||:|::.|:|...|..:..:|||..|..:.:..: :|||:.::||.|||
Mouse     5 HKEHLYKLLVIGDLGVGKTSIIKRYVHQNFSSHYRATIGVDFALKVLHWDPETVVRLQLWDIAGQ 69

  Fly    89 ERYHSLAPMYYRGAQAAIVVYDIQNQDSFQRAKTWVKEL-HKQASPN---IVIALAGNKAD---- 145
            ||:.::..:|||.|..|.:|:|:....:|:....|..:| .|...||   :.:.|..||.|
Mouse    70 ERFGNMTRVYYREAMGAFIVFDVTRPATFEAVAKWKNDLDSKLTLPNGKPVSVVLLANKCDQGKD 134

  Fly   146 -LSNIRVVEFDEAKQYAEENGLL-FMETSAKTGMNVNDIFLAIAKKLPKND 194
             |.| ..::.|   |:.:|:|.: :.|||||..:|:::....:.|.:..|:
Mouse   135 VLMN-NGLKMD---QFCKEHGFVGWFETSAKENINIDEASRCLVKHILANE 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab5	NP_001259925.1	Rab5_related	29..191	CDD:206653	54/172 (31%)
Rab38	NP_082514.4	Rab32_Rab38	10..208	CDD:206692	55/176 (31%)
		RAB	10..180	CDD:197555	54/173 (31%)
		Effector region. /evidence=ECO:0000250	38..46		3/7 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910