Protein Alignment Rab5 and RALB

DIOPT Version :9

• Sequence 1: NP_001259925.1
• Gene: Rab5 / 33418
• FlyBaseID: FBgn0014010
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_001356329.1
• Gene: RALB / 5899
• HGNCID: 9840
• Length: 206
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 63/212 - (29%)
• Similarity: 110/212 - (51%)
• Gaps: 19/212 - (8%)

  Fly    16 AQRPNGTSQNKSCQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTICIEDTVVKF 80
            |.:..|  |:.....|::::|...||||:|.|:|:..:|.|..|.|...:: .:.:.::...|:.
Human     3 ANKSKG--QSSLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSY-RKKVVLDGEEVQI 64

  Fly    81 EIWDTAGQERYHSLAPMYYRGAQAAIVVYDIQNQDSFQRAKTWVKEL--HKQASPNIVIALAGNK 143
            :|.||||||.|.::...|:|..:..::|:.|...:||.....:.:::  .|.....|.:.:.|||
Human    65 DILDTAGQEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKAEEDKIPLLVVGNK 129

  Fly   144 ADLSNIRVVEFDEAKQYAEENGLLFMETSAKTGMNVNDIFLAI-----AKKLPKNDGANNQGTSI 203
            :||...|.|..:||:..|||.|:.::||||||..||:.:|..:     .||:.:|...|.:.:|
Human   130 SDLEERRQVPVEEARSKAEEWGVQYVETSAKTRANVDKVFFDLMREIRTKKMSENKDKNGKKSS- 193

  Fly   204 RPTGTETNRPT--NNCC 218
                  .|:.:  ..||
Human   194 ------KNKKSFKERCC 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab5	NP_001259925.1	Rab5_related	29..191	CDD:206653	54/168 (32%)
RALB	NP_001356329.1	RalA_RalB	15..178	CDD:206710	52/163 (32%)
		Effector region	43..51		2/7 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	180..206		7/32 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910