Protein Alignment Rab5 and RALA

DIOPT Version :9

• Sequence 1: NP_001259925.1
• Gene: Rab5 / 33418
• FlyBaseID: FBgn0014010
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_005393.2
• Gene: RALA / 5898
• HGNCID: 9839
• Length: 206
• Species: Homo sapiens
• Alignment Length: 207
• Identity: 63/207 - (30%)
• Similarity: 106/207 - (51%)
• Gaps: 9/207 - (4%)

  Fly    16 AQRPNGTSQNKSCQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTICIEDTVVKF 80
            |.:|.|  ||.....|::::|...||||:|.|:|:..:|.|..|.|...:: .:.:.::...|:.
Human     3 ANKPKG--QNSLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSY-RKKVVLDGEEVQI 64

  Fly    81 EIWDTAGQERYHSLAPMYYRGAQAAIVVYDIQNQDSFQRAKTWVKE-LHKQASPNIVIALAGNKA 144
            :|.||||||.|.::...|:|..:..:.|:.|...:||.....:.:: |..:...|:...|.|||:
Human    65 DILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKS 129

  Fly   145 DLSNIRVVEFDEAKQYAEENGLLFMETSAKTGMNVNDIFLAIAKKL---PKNDGANNQGTSIRPT 206
            ||.:.|.|..:|||..||:..:.::||||||..||:.:|..:.:::   ...|.....|...|.
Human   130 DLEDKRQVSVEEAKNRAEQWNVNYVETSAKTRANVDKVFFDLMREIRARKMEDSKEKNGKKKRK- 193

  Fly   207 GTETNRPTNNCC 218
             :...|....||
Human   194 -SLAKRIRERCC 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab5	NP_001259925.1	Rab5_related	29..191	CDD:206653	52/165 (32%)
RALA	NP_005393.2	RalA_RalB	15..177	CDD:206710	52/162 (32%)
		Effector region	43..51		2/7 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910